Research - Laboratory/Non-Laboratory, Staff/Administrative
Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
The Department of Radiation Oncology at the Washington University School of Medicine has an opening for a Senior Research Technician in the Division of Cancer Biology. The laboratory projects will involve a wide range of collaborative work on molecular biology, histopathology, in vitro assays, gene expression and next generation sequencing analysis, in vivo mouse model studies, live cell imaging, and analysis of patient tumor specimens. This position independently performs complex research studies, experiments and assays. Expected to interpret data and to generate figures to be used in manuscripts and grant applications. After a period of training, will also be expected to present data at lab meetings and group research meetings.
Role of SERPINB3 in radiation response and recurrence in cervical cancer and other solid tumors.
Role of lysosome in radiation-induced death.
Molecular mechanisms of tumor immunity in radiation resistant tumors.
PRIMARY DUTIES AND RESPONSIBILITIES:
Performs complex analysis/projects according to research protocols, explaining methods and procedures to other technicians.
Provides for data entry and current data files on research projects. Monitors data to ensure consistent quality.
May perform preliminary statistical analysis of data.
Performs cell culture, Western blots, cloning, DNA/RNA isolation, molecular techniques, etc.
Performs studies with animals and performs in vitro studies, such as cell proliferation assays, apoptosis, etc.
Assures compliance with established safety procedures and maintains required documentation on laboratory and specimen conditions.
Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.
Assists in the training and development of technicians, acting as a group leader.
At least three years of post-bachelor's experience in molecular biology, immunology or a related field.
Experience in molecular biology, immunology or a related field.
Experience with small animal models (mice), as well as molecular biology techniques. Techniques include: murine xenograft and orthotopic tumor models, DNA cloning, ELISA, flow cytometry, Western Blot, immunohistochemistry, immunofluorescence, and live cell confocal microscopy.
Expertise in cancer biology and/or host and tumor immunology are considered a strength, but training will be provided as needed.
Demonstrated ability to work independently and communicate in a collaborative manner with laboratory staff and investigators.
Ability to maintain complete and organized records/reports.
Working knowledge of computer software and general lab equipment.
Master’s degree with two years of experience in a laboratory setting or an equivalent combination of education and experience equaling seven years.
This position is full-time and works approximately 40 hours per week.
Department Name/Job Location:
This position is in the Department of Radiation Oncology. This position is for the Medical School Campus.
Applicant Special Instructions:
This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
The hiring range for this position is $17.00 - $22.96 per hour.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.