Research - Laboratory/Non-Laboratory, Staff/Administrative
The Department of Laboratory Medicine and Pathology serves as a regional resource for clinical laboratory services required for patient care, research and educational programs in laboratory medicine and pathology. The department now employs 900 people who work at the award-winning University of Washington Medical Center (ranked among the top medical centers in the United States as rated by U.S. News & World Report), Harborview Medical Center (the region's only Level I Trauma center, known for innovations and excellence in trauma care and its centers of emphasis: Trauma, Burn, Neurosciences, AIDS/STD CARER, and mentally- and medically- vulnerable populations.), and many other clinical and research facilities in the area. The University of Washington (UW) is proud to be one of the nation’s premier educational and research institutions. Our people are the most important asset in our pursuit of achieving excellence in education, research, and community service. Our staff not only enjoys outstanding benefits and professional growth opportunities, but also an environment noted for diversity, community involvement, intellectual excitement and natural beauty.
Our Laboratory Medicine and Pathology department has an outstanding opportunity for a full-time (100%) RESEARCH SCIENTIST 2. The person in this role will perform routine laboratory procedures and support research and development of analytical chemistry techniques to quantify proteins and small molecules in complex mixtures, including urine, serum, plasma, cell culture, blood spots, and frozen and preserved tissues.
One of the overarching goals of the Hoofnagle lab is development of reference method procedures for proteins in complex mixtures to serve as the gold standard for patient care and clinical research. This individual will work with clinical technologists and research scientists to design and develop novel clinical laboratory tests and perform routine testing in support of clinical research studies.
Develop, validate, and implement new LC-MS assays to quantify proteins and small molecules from typical clinical chemistry sample types for research and/or diagnostic purposes.
Independently perform a variety of laboratory techniques (e.g. affinity purification, tryptic digestion, solid-phase-extraction, HPLC-MS, ELISA, etc.). Perform established assays using targeted proteomics and metabolomics technologies for the sensitive and specific quantification of proteins and small molecules.
Analyze experimental data with various software and analysis tools.
Contribute, analyze, and present research data using summary graphs for publication and grant submission, present and update research progress at lab meeting or joined group settings.
Optimize protocols and troubleshoot experiments as necessary to generate relevant data.
Continuously evaluate existing methods with an eye toward improving data quality, reducing costs, and/or improving turn-around-time.
Perform work accurately and precisely; recognize, correct, and document errors when they occur.
Monitor assignments and projects to ensure they are completed within specified time frame; accommodate schedule changes to cooperatively accomplish required daily work.
Maintain complete, accurate, legible records. Author, review, and revise SOP's.
Provide ongoing feedback and updates to supervisor/project coordinator and actively solicit input on overcoming roadblocks and impediments to success.
Train new employees and guest technicians in experimental procedures and assays, instrument maintenance, laboratory safety, and general lab procedures.
Perform routine instrument maintenance as well as troubleshooting; serve as point-of-contact with service engineers.
Coordinate sample receiving/shipments with collaborators; assist with sample tracking, inventory maintenance, data entry, and database updating.
Prepare and verify reagents; monitor and order supplies.
Perform other duties as assigned.
Requirements: Bachelor’s degree in Life Sciences (including chemistry, biophysics, biochemistry, etc.) AND a minimum of three years of experience working in a laboratory setting.
Additional Requirements: Must be able to communicate effectively both verbally and in writing.
Demonstrated ability to think and work independently.
Strong organizational skills and a keen attention to detail.
Ability to clearly express oneself both verbally and in writing, and have the capacity to carefully analyze the data they generate.
Comfortable working in a team environment, and have the ability to manage their own workload effectively.
Careful and fastidious.
Strong computer skills with a working knowledge of general MS Office applications.
Previous experience using mass spectrometry and/or developing quantitative mass spectrometry-based methods.
This position provides opportunities to work in a fast-paced, challenging, diverse and rewarding environment. As an employee you will enjoy generous benefits and work/life programs. For detailed information on Benefits for this position, click here.
Founded in 1861, the University of Washington is one of the oldest public institutions in the west coast and one of the preeminent research universities in the world. The University of Washington is a multi-campus university comprised of three different campuses: Seattle, Tacoma, and Bothell. The Seattle campus is made up of sixteen schools and colleges that serve students ranging from an undergraduate level to a doctoral level. The university is home to world-class libraries, arts, music, drama, and sports, as well as the highest quality medical care in Washington State and a world-class academic medical center. The teaching and research of the University’s many professional schools provide undergraduate and graduate students the education necessary toward achieving an excellence that will serve the state, the region, and the nation. As part of a large and diverse community, the University of Washington serves more students than any other institution in the Northwest.