Research - Laboratory/Non-Laboratory, Staff/Administrative
Sr. Research Scientist-Basic Life Science (Fixed-Term)
Job Number: 86893
**Fixed-Term Position** The Fantl Lab at Stanford University School of Medicine studies human tumors with translational endpoints with the over-arching goal to dramatically shorten the time from bench to bedside. We use multi-parameter single cell technologies (mass cytometry/CyTOF and imaging) to comprehensively characterize human tumors on a cell-by-cell basis; specifically ovarian, kidney and prostate. Two areas of focus of the lab are tumor-immune interactions and the DNA-damage response. To date, work from our and other labs have demonstrated that multi-parameter single cell technologies have provided an unprecedented level of mechanistic detail not only revealing further unappreciated complexity of tumor ecosystems, but directing us toward more meaningful novel biomarkers. These are highly likely to guide far more beneficial treatment regimens for cancer patients. We work collaboratively in multidisciplinary teams. We synergize with bioinformaticians for integrating large datasets and clinicians to ensure the acquisition of tumor tissue and also to keep us on track as to what will make a difference to patients. We are seeking a highly motivated, committed and creative Senior Scientist to oversee the general running of the lab. The preferred candidate is an immunologist and/or cancer biologist. The candidate will be adept at working with multiple assay formats, assay troubleshooting, problem-solving and data analysis/interpretation in addition to driving multiple research projects. He/she will apply CyTOF to clinically annotated tumors and blood samples and use integrative computational tools to provide novel insight about disease mechanism and develop potential biomarkers. Projects include, but are not limited to: i) therapeutic resistance in ovarian cancer ii) predictive biomarkers for women with ovarian cancer likely to respond to PARPis iii) understanding the role of defects in BRCA1/2 and other DNA damage response genes with the tumor immune infiltrate in ovarian cancer iv) predicting response of renal cell carcinoma patients to immunotherapy v) determining which men with localized prostate cancer will develop aggressive disease. Edwjfantl@stanford.edu
'Stanford University is an equal opportunity employer and is committed to increasing the diversity of its faculty and academic staff. It welcomes nominations of and applications from women and members of minority groups, as well as others who would bring additional dimensions to the University's research, teaching and clinical missions.'
Location: School of Medicine, Stanford, California, United States Schedule: Classification Level:
Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.
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Located between San Francisco and San Jose in the heart of Silicon Valley, Stanford University is recognized as one of the world's leading research and teaching institutions. Leland and Jane Stanford founded the University to "promote the public welfare by exercising an influence on behalf of humanity and civilization." Stanford opened its doors in 1891, and more than a century later, it remains dedicated to finding solutions to the great challenges of the day and to preparing students for leadership in a complex world. The University's thriving diverse community is comprised of nearly 7000 undergraduate students, 12000 graduate students, 2000 faculty members, 1900 postdoctoral scholars, and over 11,000 academic and administrative staff in seven schools including several interdisciplinary research centers and institutes. The campus spreads over 8000 contiguous acres and nearly all undergraduates live on campus. Stanford offers bachelor's and master's degrees in addition to doctoral degrees (PhD, MD, DMA and JD) plus a number of professional and continuing education programs and certifications. More at http://facts.stanford.edu and http://www.stanford.edu. Stanford is an equal empl...oyment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stanford also welcomes applications from others who would bring additional dimensions to the University’s research, teaching and clinical missions.