Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are composed of biologists, chemists, biomedical engineers, computationalists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy.
CEDAR is committed to increasing the diversity of the campus community. We at CEDAR are dedicated to promoting inclusion and multiculturalism to build a successful organization by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires unproven, out-of-the-box thinking. Our research is milestone driven to ensure that each project is fulfilling its stated goals.
As a Sr.Research Assistant , you will support molecular and cellular biology work at CEDAR. You will be part of a multidisciplinary team developing novel approaches for early detection of cancer. Major projects will involve interrogation of biological specimens using methods in cellular biology, including fluorescence microscopy, molecular biology, and biochemistry. An understanding of how to develop assay protocols for high throughput experiments and a mechanical and/or computational understanding required for complex equipment use would be preferred. Major roles for the candidate will involve: providing support in cellular and molecular biology experiments, assisting in experimental design, training of RA1s and RA2s, and organizing samples, datasets and studies; support of complex robotic and automated equipment; responsible for engaging with researchers to help enable optimal use of robotic or automation supported equipment (e.g., Hamilton liquid handling devices such as STARlet and Star, ECHO550 Labcyte Access robotic acoustic liquid handling device system, and in vivo imaging system); as needed and depending on experience, contribution to method developmet and more advanced analytic routines including those related to single-cell biology.
Every Knight Cancer employee is expected to embody our guiding principles:
We act BOLDLYBreakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
We SUPPORT each otherRespect leads to trust, which leads to excellence
We work as a CONNECTED team We must leverage our collective brain power to conquer cancer because no one individual can do it alone
Under the guidance of a team leader, perform and be responsible for technical procedures and research projects such as ELISA, electrophoresis, mammalian cell culture, nucleic acid extraction, immunofluorescence, Western blotting, subcloning, etc.
Work with researchers within CEDAR, across the Knight and OHSU to enable optimal use of various robotic driven research equipment that is located within the Knight Cancer Research Building. This position will: 1) be responsible for maintaining the shared equipment to a working standard, 2) facilitate and enable customized protocol development for individual researchers, and will 3) oversee the booking system and aid with billing for equipment usage. The current list of equipment includes two Hamilton liquid handling devices (STARlet and Star) and the In vivo imaging system (IVIS) for live animal imaging. This aspect of the position is expected to expand over time as new equipment is installed.
Operate a variety of instruments and scientific equipment, including immunofluorescence microscopy, flow cytometry etc.
Collect, record, organize and verify the accuracy of data; keep detailed and accurate laboratory records; tabulate data, perform calculations, prepare charts, graphs, reports and manuscripts. May use software applications to assemble, manipulate, format and/or perform statistical analysis of data.
Special projects as assigned, may be responsible for one or more areas of support for all CEDAR
Bachelors degree with major courses in field of research and 1 - 3 years of relevant experience
>3 years, molecular and cellular biology or closely related discipline
Experience with tissue culture, molecular biology technics (cloning, qPCR), and basic biochemistry (western blot, protein pull-downs)
An understanding of, and ideally previous experience with cancer biology.
Ability to prioritize multiple tasks at one time
Excellent communication, analytical and organizational skills: both written and verbal
Ability to learn new methods quickly, to work independently and as part of a team while being collaborative in resolving problems
Intermediate skills with Microsoft Office (Excel, Outlook, Access, Word, and PowerPoint)
Demonstrated ability to learn new and innovative processes quickly.
Demonstrated knowledge of basic computer programing languages to enable programming for robotic equipment
>5 years, molecular and cellular biology or closely related discipline
Experience in producing retroviruses or lentiviruses.
Experience in CRISPR/Cas9 genome editing
Skills in next-generation sequencing
Experience in flow cytometry and confocal microscopy
Apply online. Please be sure to upload a Cover Letter and Resume/CV.
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or email@example.com.
As the state's only health and research university, OHSU brings together patient care, research, education of the next generation of health care providers and scientists and community service to improve the health and well-being of all Oregonians.The university is a conduit for learning for more than 2,800 students, providing training to interns, residents and fellows in postgraduate medical and research. It is the only place in Oregon that grants doctoral degrees in medicine, dentistry and nursing. OHSU cares for more than 251,000 patients each year from around the region and takes a leadership role in contributing to solutions involving the health of the state and the nation, such as health care access and transparency, ethics and workforce shortage. Beyond providing critical health care services, quality education and cutting-edge research, OHSU also is a key economic and social force in the Northwest. With an annual operating budget of $2.06 billion and more than 14,000 employees, OHSU is Portland?s largest employer. Its size contributes to its ability to provide... many services and community support activities not found anywhere else in Oregon. For more information visit http://www.ohsu.edu/xd/about/index.cfm