RESEARCHER POSITION IN PROTEOMICS AND CANCER BIOLOGY
The lab of professor Nevan Krogan in the Department of Cellular and Molecular Pharmacology (CMP) at the University of California, San Francisco is recruiting a full-time Researcher with expertise in cancer systems. This position will join the Cancer Cell Map Initiative (CCMI), a multi-disciplinary team of systems and cancer biologists, as well as clinicians. The CCMI group aims to comprehensively map the gene and protein networks underlying cancer and hopes to develop technologies leading to precision medicine.
As a part of the CCMI, the successful candidate will lead projects involved in the proteomic efforts for CCMI including large-scale protein-protein interaction (PPI) studies, phosphoproteomic kinase activity profiling, and drug screening studies investigating cancer dependency on their kinome profile to identify drug synergies. As an independent investigator, the candidate will: (1) perform proteomics experiments; (2) analyze proteomic data (3) develop and implement drug screening strategies; (4) provide scientific oversight of the projects including review and advice on experimental design, data interpretation, and long-term planning to her or his team and colleagues; and (5) write manuscripts and applications for federally sponsored research.
The applicant must have a PhD and/or MD degree with experience in cancer biology, systems biology, biochemistry or a related field. They should also have a strong track record of developing and leveraging innovative proteomic-based systems with emphasis on cancer biology and phosphoproteomic approaches. Candidates should have research expertise in mapping protein interaction networks, and synergistic drug screening strategies. Experience with mouse models, developing and applying multiscale studies using primary samples from cancer patient cohorts and data analysis tools such as R is a plus.
Evidence of publishing in high impact peer-reviewed journals is essential. Experience in writing and submitting sponsored research proposals is desired. Applicants will have strong written, verbal, and presentation skills and an ability to communicate and work in an interdisciplinary team environment. In addition, she or he should have excellent management skills with experience mentoring and advising students and trainees.
Extensive experience with molecular biology lab techniques and cell culture
Experience in designing and performing phosphoproteomic experiments
Experience in proteomic data analysis
Demonstrated experience as a research project lead
Manage multiple diverse and collaborative projects between multiple laboratories
Excellent oral and written communication skills
High productivity and successful record publishing in high impact journals
Experience in high throughput drug screening
Handling of mouse models and patient derived xenografts
Multiscale data generation and analysis
Data analysis using R
Data visualization and analysis using Cytoscape
Success in securing external research funding
UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.