Summary of Position: We are seeking a postdoctoral associate to join the new federally-funded Center for Neural Circuits in Addiction. You will help us overcome current limitations of cell-type specific gene delivery in the brain, and engineer novel Adeno-Associated Virus (AAV) vectors for the experimental study of the anatomical, cellular, and molecular bases of addiction. We have developed composite antibody−AAV nanoparticles that enable programmable receptor-mediated gene delivery. You will join a team that uses a combination of deep mutagenesis, machine learning, and advanced biomanufacturing to determine the mechanistic and structural basis of antibody-AAV composite function, and to validate their utility for precise gene delivery to neural circuits in vivo. Applicants from neuroscience, virology, cell biology & biochemistry, (biomedical) engineering and related fields are welcome. We are start-up laboratory in which you will find the freedom and resources to succeed, and the mentorship to become a well-rounded independent researcher.
Essential and Other Functions:
80% Plan and conduct experiments (essential) In consultation with the PI, plan and execute a research strategy to develop neural circuit-specific AAV using approaches and techniques from biochemistry, molecular and cell biology, biomedical engineering, and computational biology.
8% Scientific Writing (essential) Write manuscripts to disseminate research results. Write applications for scientific fellowships and grants (e.g., K99)
8% Career development, Networking, Continuing Education (essential) Participate in lab/department/national/international scientific meetings, symposia, seminar series, journal etc.
4% Trainee supervision and mentoring (secondary) Supervise and mentor undergraduate and graduate students in the lab.
Note: These are not positions to which permanent residency can be granted for international appointees.
The University of Minnesota offers a comprehensive benefits package including:
Competitive wages, paid holidays, vacation and sick leave
Low cost medical, dental, and pharmacy plans
Health care and dependent daycare flexible spending accounts
Excellent retirement plans with employer match
Disability and employer paid life insurance
Wellbeing program with reduced insurance premiums
Tuition reimbursement opportunities covering 75%-100% of eligible tuition
Student loan forgiveness opportunity
Opportunities for growth and promotion
Employee Assistance Program
As a Postdoctoral Associate at the University of Minnesota, you are considered to be in an academic professional position governed by academic policies. The link to governing policies is at http://policy.umn.edu/sites/policy.umn.edu/files/appendix/postdocappoint_appa.pdf
Required Qualifications PhD candidate in biological sciences, neuroscience, bioengineering or recent PhD graduate (within past 2 years). Experience with tissue culture, molecular biology, and biochemistry. Established publication record in the form of first-author publication(s).
Preferred Qualifications PhD in neuroscience or biomedical engineering or another quantitative biological discipline. Experiences with AAV engineering or molecular protein engineering techniques and high-throughput screening. Foundational knowledge of computational biology for quantitative data analysis and familiarity with scientific programming languages (e.g., R or Python). Outstanding achievements in their doctoral research, established publication record in the form of first-author publications, ambitious scientific goals, and independent research abilities.
Internal Number: 337020
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.