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The Barry laboratory , within the Fred Hutchinson Cancer Research Centers Translational Research Program, is looking for a talented post-doctoral fellow with extensive expertise in the realm of tumor immunology. The Barry lab focuses on understanding how the immune system responds to cancer and can be manipulated to treat cancer. Our studies utilize human immunology, murine models of cancer, state-of-the-art imaging techniques, RNA sequencing techniques, and immunological techniques to explore the role of the innate immune system in controlling immune responses to cancer. We focus our research on understanding how the innate immune system, specifically dendritic and natural killer cells, shape immune responses to cancer and patient responses to common immunotherapies (see Barry et al., 2018 PMID: 29942093).
The candidate will spearhead a project with the following goals:
to define the molecular and cellular mechanisms regulating natural killer and dendritic cell abundance in the tumor microenvironment in human and mouse tumors
To develop and undertake broad immune profiling studies of human tumors to interrogate the innate immune response to cancer and its role in regulating responses to immunotherapy
A Ph.D. in the life sciences with a focus on immunology or tumor immunology is required. A strong publication record as well as eligibility and desire to apply for future fellowships are required. The candidate must also be experienced in essential techniques to characterize and profile immune cells and to gauge their function. A candidate with experience in live cell imaging, human immunology, and experience working in murine tumor or metastasis models is strongly desired.
The successful candidate must have excellent communication and organizational skills, the ability to develop creative approaches to experimental design, and thrive both in independent research and while working collaboratively with other fellows, graduate students, and staff in the lab.
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At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.