In this exciting role, you will include the development of new methods for crystallographic and cryo-EM structure determination and completion in the context of the PHENIX program and the Computational Crystallography Toolbox (cctbx). Your duties will also include testing, documentation writing, extensive interaction with users and other developers, and publishing scientific papers. You will work under the general direction of the Principal Investigator (PI; Paul Adams) for this project.
What You Will Do:
Development of crystallographic and cryo-EM algorithms within the Computational Crystallography Toolbox (cctbx) and Phenix.
Implementation of new algorithms using a combination of C++ and Python in consultation with the lead PI and other members of the Phenix team.
Performing extensive and advanced self-guided data analysis and testing of algorithms using large-scale computing resources.
Publication of research results in scientific journals and presentation of results at scientific meetings.
Responding to user questions and bug reports as needed.
Writing extensive documentation of computation procedures for other developers and end-users.
This position requires interaction with PIs, postdocs, other scientists and external collaborators involved in the PHENIX project.
Day-to-day supervision of undergraduate, intern, or graduate students as necessary to meet research goals.
Actively participate in group meetings.
What Is Required:
Ph.D. in computational crystallography, biophysics, chemistry, computer science, or related field is strongly preferred.
Demonstrated expertise with computational methods for structural biology.
First-author publications in the area of structural biology.
Experience writing documentation.
Familiarity with software development: a priority is the Python scripting language, with experience in C++ desirable.
Familiarity with the process of solving macromolecular structures.
Solid interpersonal skills and the ability to work in a team environment are critical.
The posting shall remain open until the position is filled.
This is a full-time career appointment.
M-F, exempt (monthly paid) from overtime pay.
There are multiple openings for this position.
Salary is commensurate with experience.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be primarily performed at Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA.
Learn about us!
Molecular Biophysics and Integrated Bioimaging
Mission: To generate a mechanistic and predictive understanding of biological processes, by developing and applying molecular- and meso-scale visualization and advanced spectroscopies, enabling the control, manipulation and generation of biological function.
Vision: To generate fundamental knowledge that inspires a mechanistic understanding of biological processes, with the ultimate goal of manipulating, controlling, and creating biological functions in order to solve national challenges in energy, environment, health and biomanufacturing.
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Working at Berkeley Lab has many rewards including a competitive compensation program, excellent health and welfare programs, a retirement program that is second to none, and outstanding development opportunities. To view information about the many rewards that are offered at Berkeley Lab- Click Here.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law.
Lawrence Berkeley National Laboratory encourages applications from women, minorities, veterans, and other underrepresented groups presently considering scientific research careers.
Internal Number: 90563
About Lawrence Berkeley National Laboratory
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.