The University of Cincinnati College of Medicine, Department of Molecular Genetics is seeking outstanding Postdocs to join an interdisciplinary team on an exciting and ambitious new project using cutting-edge techniques to study how genes associated with neurodegeneration or neurorepair contribute to disease and recovery after CNS injury in a cell-type-specific manner. The Luo lab utilized genetic modification and pharmacological modulations to study the role of key molecular pathways in determining neuronal survival and neuroregeneration after injury. A wide range of techniques will be involved including animal disease model, genetic targeting using CRISPR and human induced pluripotent stem cells (hiPSCs) and single-cell or bulk RNA sequencing. Overall, this project represents an exciting opportunity to leverage recent advances in stem cells, CRISPR, and single cell sequencing technologies to drive innovation in disease-relevant cell models (including stroke and Parkinson’s disease). We encourage anyone with the Essential Skills to apply and especially welcome applications from individuals with expertise in the Ideal Skills listed.
Essential Skills • PhD or equivalent experience in a relevant subject area e.g. Cell Biology, Molecular Biology, Neuroscience, or a closely related field. • Exceptional interpersonal, and written and oral communication skills. • Significant practical experience with core techniques in cell biology (e.g. mammalian cell culture and cellular assays) and molecular biology (e.g. genetics and sequencing) • Ability to work independently, collaboratively, and productively, as supported by a strong track record of first-author and collaborative papers in peer-reviewed journals • Ability to develop, troubleshoot, and implement new assays and techniques
Ideal Skills • Practical and theoretical expertise in neuroscience, neurodegeneration, disease modelling, and/or neuroinflammation • Practical expertise with FACS sorting and RNAseq. • Experience with animal models (surgical skills and behavioral analysis). • Practical expertise with gene editing using CRISPR technique.
Ph.D., M.D., or M.D./Ph.D., required.
Requires an in-depth knowledge of a specialized field, process, or discipline.
Good oral and written communication skills.
Ability to work and collaborate effectively with students, faculty and staff from a variety of culturally diverse backgrounds.
The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.
As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).
The University of Cincinnati is an Affirmative Action / Equal Opportunity Employer / Minority / Female / Disability / Veteran.
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Internal Number: 49521-en_US
About University of Cincinnati
HISTORY IN BRIEF - The University of Cincinnati is a public urban serving research institution that was founded in 1819 and today is one of the country’s largest universities offering more than 350 academic programs to more than 44,000 students. UC has many top ranked programs in areas such as Music and Arts, Medical and Human-Services, Criminal Justice and more. Located in an urban setting, UC is close to the heart of Cincinnati and allows easy access for students to enjoy all that the city offers. UC is also the alma mater of many notables such as President William Howard Taft; Albert Sabin, developer of the oral polio vaccine; Astronaut Neil Armstrong and Mary Weinberg, 2008 Olympic gold medalist. UC is classified as a Research University (Very High Research Activity) by the Carnegie Commission and is ranked as one of America’s top 35 public research universities by the National Science Foundation. UC jumped 17 spots in the U.S. News & World Report rankings in the past two years alone. In addition to being named a “green university” by Princeton Review, UC has been named one of the world’s most beautiful campuses by Forbes and Delta Sky magazines. Learn more at www.uc.edu.MISSIO...N STATEMENT - The University of Cincinnati serves the people of Ohio, the nation, and the world as a premier, public, urban research university dedicated to undergraduate, graduate, and professional education, experience-based learning, and research. We are committed to excellence and diversity in our students, faculty, staff, and all of our activities. We provide an inclusive environment where innovation and freedom of intellectual inquiry flourish. Through scholarship, service, partnerships, and leadership, we create opportunity, develop educated and engaged citizens, enhance the economy and enrich our University, city, state and global community.