Recruiting a forward thinking and innovative lab scientist who shares the dual-vision of advancing the field of adoptive cellular therapy and rapidly translating their work for clinical evaluation. You will use the latest advances in gene engineering and cellular manipulation, and work in close contact with the Connell O'Reilly GMP Cell Manipulation Core Facility. Post-doctoral research fellows will gain experience at every step of the process from conception to transgene design / genetic engineering (lentiviral and/or CRISPR based), through reduction to practice, in vitro and in vivo screens, and ultimately working with partners to coordinate GMP manufacturing of clinical reagent for translation to the clinic.
Position is in the lab of Dr. Eric Smith, Director of Translational Research, Immune Effector Cell Therapies at Dana Farber. Dr. Smith is deeply committed to the growth and success of each trainee that joins the lab. He believes that mentorship is not something that happens in the background as trainees pursue their research, but should be intentional, thought out, and personalized for each member of the group. He spends the time to meet trainees' individual needs, not only in terms of their scientific growth, but also with a focus on career goals and development. He has vivid recollection in terms of what to prioritize in this day and age to most successfully advance a trainee's career. The Smith lab's research is multi-disciplinary and exceedingly collaborative. To this end, a mentorship plan will be developed involving a senior faculty member with complimentary expertise. Trainees will further benefit from Dr. Smith's prior experience translating cell therapy inventions from the lab to the clinic, which has resulted in 9 awarded or pending patents, licensing/collaborations with industry, and multiple products stemming from bench work reaching patients.
The Dana Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must.
This full-time position will also include some general lab duties as outlined below.
Smith Lab Website: ericsmithlab.org
Design and perform experiments both individually and collaboratively;
Prioritize research plan
Manage the work efforts of at least one individual contributor(s)
Provide advice and training for junior members of the lab
Work on problems of diverse scope
Develop, modify, and improve standard lab operating procedures
Select methods and techniques for obtaining solutions
Analyze and present data both informally and formally
Manage basic science and translational projects
Innovative, forward-thinking critical scientist
Minimum 2 year commitment
Excellent communication skills (written and verbal)
Enjoy working in a team environment with a wide variety of faculty and staff
Those with relevant and/or complimentary expertise, including but not limited to the following skills are encouraged to apply:
-Single cell RNAseq
-Advanced flow cytometry or CyTOF
-Humanized mouse models
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.
Internal Number: 2020-19508
About Dana-Farber Cancer Institute
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to under-served members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.