Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
This research opportunity is with the McElrath laboratory, HIV Vaccine Trials Network (HVTN) and Coronavirus Prevention Network (CoVPN). Our lab is recruiting a research technician to primarily perform assays to characterize antiviral T and B-cell responses. The incumbent will be expected to perform complex research assays, utilizing flow cytometry to evaluate vaccine-induced cellular immune responses in vaccine recipients participating in clinical trials of investigational vaccines for SARS-CoV-2/COVID-19, HIV, malaria, tuberculosis (MTB), and Ebola. They will be responsible for performing and coordinating the assays with other technicians and analyzing the data. They will interpret and report on experimental results and assist with data presentation. They will assist in writing laboratory SOPs, reports, and other documentation. They will report to a project manager and work closely with a technical team.
The HVTNs mission is to facilitate the process of testing preventive vaccines against HIV/AIDS or other infectious diseases. The organization conducts all phases of clinical trials from evaluating experimental vaccines for safety and the ability to stimulate immune responses through to testing vaccine efficacy. The HVTN laboratory is responsible for conducting laboratory-based studies to evaluate the immunogenicity of investigational vaccines.
Maintain a high level of accuracy for all work
Work well as team-member, participate in positive communication, and foster an environment that allows all laboratory staff to work well together
Independently perform flow cytometry, FACS sorting, and other experimental assays, such as MSD, ELISpot and ELISAs
Perform flow cytometry (intracellular cytokine staining and FACS sorting), ELISPOT and MSD/Luminex/ELISAs for characterization and monitoring of T and B cell responses
Proactively prepare reagents for experiments and for general lab use
Troubleshoot and optimize experimental methods, results and analysis
Maintain accurate documentation for experiments and quality control for the laboratory
Carry out maintenance, trouble-shooting and QC of laboratory equipment
Review the literature to stay informed on the HIV vaccine field or immunological assays
May perform data analysis, interpretation, and statistical analyses
Other duties as assigned
A bachelors degree in immunology or biological science and preferably 2 years of laboratory experience.
Motivation, adaptability and ability to be a strong team player are essential, as is a keen interest in the SARS-CoV-2/COVID-19 & HIV vaccine field.
Specific experience with flow cytometry, immunology, cellular assays, and tissue culture are preferred.
The candidate must be someone with great attention to details, well-organized, self-motivated, and able to efficiently manage time and experiments.
Experience in a GLP or GCLP setting or clinical experience, with strong documentation skills is also desirable.
Applicants must be willing to work with biohazardous/infectious agents (e.g., bloodborne pathogens, including SARS-CoV-2/COVID-19 & HIV-1) and also be flexible and willing to work evenings and weekends per work schedule.
Salary will be commensurate with appropriate experience.
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At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.