Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
The Cancer Biology Division within the Department of Radiation Oncology consists of a core group of clinical, biology, physics and computational science investigators who use both archived and prospectively collected tumor samples and data on normal tissues to ask fundamental questions about radiotherapy efficacy and cancer biology. There is a strong focus on the identification of biomarkers that can be used to risk-stratify cancer patients and to identify patients for targeted therapies.
Department Name/Job Location:
This position is in the Department of Radiation Oncology. This position is for the Medical School Campus.
The Bergom Laboratory at Washington University in the Division of Cancer Biology of the Department of Radiation Oncology is seeking a post-doctoral research associate with training in molecular biology and/or genetics and small animal work, preferably in the context of radiation biology and/or cardiovascular research. The laboratory focuses on identifying the genetic basis for sensitivity to cardiac radiation, as well as the mechanisms of radiation-induced cardiovascular dysfunction. Another focus of the laboratory is to identify factors in the tumor microenvironment that alter radiation sensitivity in breast cancers. The overall goal of the laboratory is to improve the therapeutic ratio of radiation therapy by increasing efficacy or radiation in the tumor, while minimizing side effects from radiation exposure to normal tissues, with a special emphasis on radiation-induced cardiac disease.
Candidates are expected to use mouse and/or rat models of radiation-induced cardiac dysfunction and genetic models and pharmacologic approaches to identify new therapeutic targets to improve outcomes of patients who are exposed to cardiac radiation as part of their cancer treatment. Models may also include tumor models examining whether changes in normal tissue radiation sensitivity alter the effectiveness of radiation therapy in tumors. Techniques employed include next generation sequencing and novel small animal and tumor imaging techniques.
PRIMARY DUTIES AND RESPONSIBILITIES:
Actively pursue research under the supervision of the PI while developing skills for independent research.
Critically analyze and summarize scientific literature.
Develop research questions, design and conduct experiments, and critically analyze data.
Communicate methods, data, and results in presentations and via manuscript writing.
Assist with grant preparation.
Doctoral degree in biology, chemistry, biomedical engineering or a related field.
Experience in tumor biology and/or cardiovascular biology.
Experience with preclinical and translational research involving animals.
Highly motivated with excellent oral and written communication skills.
Understanding of next-generation sequencing technologies.
Familiarity with radiation biology.
Post Doc Instructions:
Please do not submit an application to this posting.� To apply for this postdoctoral research opportunity, follow the directions below in �Applicant Special Instructions�.
Base pay commensurate with experience.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Applicant Special Instructions:
Please send a CV and three recommendation letters to Dr. Carmen Bergom at firstname.lastname@example.org.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.