The Bioinformatics Analyst is responsible for supporting the ever-growing computational analysis needs of the Genomics and Bioinformatics Core. The Bioinformatics Analyst works directly with core laboratory staff in an effort to provide optimal next-generation sequencing results. Responsibilities include analysis of all types of genomic, epigenomic, and transcriptomic data generated by the core, in addition to the development and modification of computational algorithms to facilitate data analysis at UB. Additional activities may include participating in manuscripts and grant applications, figure generation, and custom data mining efforts.
Specific responsibilities of the candidate include:
Day-to-day processing of the immense data being generated from Illumina based next-generation sequencing platforms.
Quality assurance, initial data processing, and storage of data generated.
Maintenance of core computational infrastructure.
Specialized downstream analysis for supporting projects and core initiatives.
Willingness to quickly adopt new technologies and analysis best practices.
Outstanding Benefits Package Working at UB comes with benefits that exceed salary alone. There are personal rewards including comprehensive health and retirement plan options. We also focus on creating and sustaining a healthy mix of work, personal and academic pursuit – all in an effort to support your work-life effectiveness. Visit our benefits website to learn about our benefit packages.
About UB The University at Buffalo is SUNY's most comprehensive public research university, and an outstanding place to work. UB amplifies ambition for faculty and staff by offering endless possibilities to achieve more. Here, people from all backgrounds and cultures challenge and inspire each other to discover, learn and succeed. Dedicated staff and engaged faculty collaborate to further knowledge and understanding, and develop tenacious graduates who are valued for their talents and their impact on global society. Visit our website to learn more about the University at Buffalo.
As an Equal Opportunity / Affirmative Action employer, the Research Foundation will not discriminate in its employment practices due to an applicant's race, color, religion, sex, sexual orientation, gender identity, national origin and veteran or disability status.
The ideal candidate will be collaborative, self-directed and possess the following:
An bachelor’s degree in Bioinformatics or closely related field with previous experience and familiarity with common NGS data file formats (FastQ, BAM).
Knowledge of Illumina based sequencing platforms (NovaSeq, NextSeq500, MiSeq).
Proficiency in linux is essential as all workflows are in a linux cluster environment.
Proficiency in the R coding language with experience using RStudio and Bioconductor.
Hands on experience processing Next-Generation Sequencing data sets from raw data to alignment (Bowtie2/Hisat2 preferred), and quantification (Subread featureCounts).
Previous experience using the DESeq2 analysis package from RNA-Seq.
Knowledge of 10X Genomics single-cell RNA sequencing and analysis (Seuratv3).
Background knowledge of wet bench techniques to aid in laboratory trouble shooting.
Outstanding communication and leadership skills, in interacting with both wet-lab and computational biologists.
A Masters degree in Bioinformatics or closely related field.
Experience in transcriptional analysis is strongly preferred.
Python coding skills strongly preferred (virtualenv, managing local packages).
Previous hands-on experience with wet bench assays a plus, but not required.
The University at Buffalo is SUNY’s most comprehensive public research university, and an outstanding place to work. UB amplifies ambition for faculty and staff by offering endless possibilities to achieve more. Here, people from all backgrounds and cultures challenge and inspire each other to discover, learn and succeed. Dedicated staff and engaged faculty collaborate to further knowl¬edge and understanding, and develop tenacious graduates who are valued for their talents and their impact on global society.