Research - Laboratory/Non-Laboratory, Staff/Administrative
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The Freedman Lab in the Division of Nephrology is seeking a Research Scientist to initiate a project using human pluripotent stem cells to develop new treatments for kidney disease, under the general guidance/supervision of Assistant Professor Benjamin Freedman. The Research Scientist will combine stem cell culture and differentiation with bioengineering, microfluidics, and pre-clinical animal models to build next-generation models of human kidney regeneration and disease. This position will be responsible for contributing to preparation of reports, papers, presentations and new proposals. He/she will contribute to positive colleague and investigator relationships through interactions on current grants. The successful applicant will also assist Dr. Freedman with mentoring of trainees.
Experimental duties include:
Cell culture – daily differentiation and maintenance of human pluripotent stem cells Microscopy – immunofluorescence, confocal, wide-field, live cell Microfluidics – bioengineering, device preparation, input/output bioanalysis Genome editing – guide RNA construction, transfection, screening Drug discovery – design and execution of high throughput screening assays Biochemistry and molecular biology – qPCR, electrophoresis, immunoblotting, cloning Computing and analysis – Illustrator, PowerPoint, Excel, Word, ImageJ, HTML Documentation – daily record of work performed in files and laboratory notebook
Contribute data and ideas for new projects
Drafting of new grants with minimal supervision
Preparation of primary research manuscripts with minimal supervision
Writing invited manuscripts
Assist in seeking/acquiring additional funding
Manage relationships with grants sponsors and progress reports
Animal care includes:
Data collection/maintenance management for rodent colony
Updating and ensuring compliance with animal welfare protocols
Oversight of junior trainees working in the animal facility
Demonstration and training of surgeries
Developing new animal protocols
Mentor research trainees and undergraduates; contribute to improvements in efficiency
Orient/train new staff
Manage projects of moderate size and scope
Assemble and organize research teams
Lead projects or project tasks toward research objectives
Inventory management for reagents/orders/cells; track expenses
Ensure compliance with lab regulations and completion of corresponding paperwork
As a UW employee, you will enjoy generous benefits and work/life programs. For detailed information on Benefits for this position, click here.
Bachelor’s degree in biology, bioengineering, biophysics or related field and at least four years of experience or equivalent combination of education and experience.
Cell culture skills and experience; strong computer skills including Excel, statistical and/or graphical software (ex. Adobe Illustrator, ImageJ, Powerpoint); excellent organizational and communication skills; ability to manage diverse tasks; flexibility in work hours; a thirst for scientific knowledge and progress; comfort working with animal model; and a high degree of integrity.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
PhD in related field.
Experience with human pluripotent stem cells, high throughput screening, genome editing (CRISPR/Cas9), or rodent microsurgery.
CONDITIONS OF EMPLOYMENT
Application Process: The application process for UW positions may include completion of a variety of online assessments to obtain additional information that will be used in the evaluation process. These assessments may include Workforce Authorization, Cover Letter and/or others. Any assessments that you need to complete will appear on your screen as soon as you select “Apply to this position”. Once you begin an assessment, it must be completed at that time; if you do not complete the assessment you will be prompted to do so the next time you access your “My Jobs” page. If you select to take it later, it will appear on your "My Jobs" page to take when you are ready. Please note that your application will not be reviewed, and you will not be considered for this position until all required assessments have been completed.
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