Research - Laboratory/Non-Laboratory, Staff/Administrative
Cellular Manufacturing 70% a. Manufacturing and characterization of immune modifying cellular products including donor-specific Apoptotic donor leukocytes for immunoregulation protocols following standard operating procedures for both allo- and xeno-islet transplantation studies with supervision. i. Isolation, culture, expansion, and characterization of lymphocytes from primary tissue (blood and spleen) following defined schedule. ii. Immunological characterization of cell therapy products and donor/recipient blood products following established protocols. b. Collect experiment data on Forms and Batch Production Records. c. Transcribing data from manufacturing documents and to existing databases, spreadsheets, and web-based applications. d. Perform routine data analysis following defined procedures. e. Assist in preparation of summary reports and assist in drafting technical reports for publication, study reports and/or research proposals. f. Assist in development of human clinical cellular manufacturing program at cGMP facility. g. Training of new staff in manufacturing processes under GRP/cGMP standards
Laboratory Support 30% a. Order and maintain laboratory supplies and equipment using University Electronic Financial System. b. Investigate and evaluate vendors and products. c. Participate in staff meetings and provide input to improve daily laboratory operations. d. Washing instruments, packing, wrapping, autoclaving material and equipment used in isolation and sterile long term culture of expanded lymphocytes. e. Assist Core Director in design and administration of databases and spreadsheets f. Maintain physical and digital inventory of tissue samples. g. Training of junior staff and students in manufacturing support processes under GLP/GMP standards
Researcher 2 Schulze Diabetes Institute Department of Surgery
All required qualifications must be documented on application materials.
Required: · Bachelor’s degree in biological sciences with at least one year of scientific (bench) research experience, or a combination of education and work experience to equal five years. · Must be willing to work a flexible work week; core lab hours are 8am to 4:30pm · Must be able to lift 50lbs by oneself, must be able to sit and stand for long periods · Must rotate on an on-call schedule for evenings, weekends, and holidays · Willingness to work with animal models
Preferred: · Experience in cellular manufacturing or aseptic/sterile/closed-system tissue culture techniques · Experience working in a FDA regulated environment (GLP/cGMP) · Experience with flow cytometry, fluorescent microscopy/imaging, and/or microplate related assays (ELISAs, FP, HTRF, FRET)
Internal Number: 336408
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