Research - Laboratory/Non-Laboratory, Staff/Administrative
Summary of Position: Study cell cycle control, in particular mitotic checkpoints and chromosome dynamics and segregation, to understand mechanisms that promote faithful genome transmission. Use cutting-edge genetic strategies in yeast and mammalian cell to generate new genotypes. Analyze cell cycle controls and progression using biochemical and microscopy-based assays. Perform biochemical fractionations for proteomic analysis. Write manuscripts and grant applications. Mentor students and lead projects.
Essential and Other Functions: 25% Genetics and Molecular Biology: Manipulation of yeast strains and human cells to derive new genotypes.
25% Biochemistry and Microscopy: Analysis of cell cycle events based on protein analysis and morphological evaluation using fluorescence and confocal microscopy. Purification of chromatin protein fractions for proteomic analysis.
25% Literature Analysis and Grant Writing: Preparation of manuscripts and grant proposals based on data generated and the current literature
25% Mentoring: Training and mentoring of graduate and undergraduate students in laboratory research
Required Qualifications: A PhD in fungal genetics specializing in cell cycle controls. A minimum of four years of post-doctoral research experience specializing in cell cycle controls. Expertise in microscopy-based analyses including live-cell imaging. A substantial publication record.
Preferred Qualifications: Extensive experience with fungal genetics, molecular biology, biochemistry and analysis using fluorescence and confocal microscopy. In particular, analysis of cell cycle events, mitosis, chromosome segregation, and cell cycle checkpoints in both yeasts and mammalian cells. Expertise in genetic engineering of mammalian cells.
Internal Number: 336387
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