Berkeley Lab's Biological Systems Engineering Divisionhas an opening for a Scientific Engineering Associate. The Scientific Engineering Associate will work with the Joint BioEnergy Institute (JBEI), Synthetic Biology Informatics and Agile BioFoundry (ABF) teams to contribute to automation engineering efforts and will apply standard engineering, scientific, and/or other technical concepts to provide technical support for biotech-laboratory equipment. The position will also occasionally perform basic and some advanced molecular biological and microbiological work pertaining to various aspects of DNA construction and sequence validation.
The successful candidate will perform assignments related to operating, programming, and repairing the instrumentation, evaluating and supporting the procurement of new instrumentation, as well as troubleshooting automation systems and instruments. The position will lead efforts to record and report DIVA DNA service costs and labor hours, and to assess researcher compliance with JBEI and ABF publications policies. The position will also contribute to scientific and technical peer-reviewed publications, and present results at scientific and technical meetings and conferences.
This position will be hired at a level 1 or 2 contingent upon level of experience, skills, knowledge, and abilities of the successful candidate.
What You Will Do:
Serve as an additional subject matter expert for lab automation aspects of JBEI and ABF R&D activities
Participate in engineering and process improvement projects to advance the JBEI and ABF missions and to gain operational efficiencies in terms of reductions in project cycle time, cost, and/or labor time
Collaborate with research personnel to design, develop, and implement automation solutions for biotechnological work processes
Utilize commercially available software, including Visual Basic, VBScript, VB.Net, VBA, and Excel as well as custom software applications (including Biomek, Biomek Method Launcher, and Semi Ex) to program robotic platforms and general laboratory equipment
Script automated workflows on robotic liquid handlers and large integrated robotic systems (e.g., a Biomek FXP Laboratory Automation Workstation integrated with microplate hotel, conveyer, incubator, centrifuge, and plate reader)
Train and collaborate with end-users on the operation of systems and tools, and support their implementation, including the development of training material, Standard Operating Procedures, and validation testing
Collaborate with vendors for the support, troubleshooting, and repair of laboratory instruments including: Liquid Handlers, Robotic Systems, Analysis Instruments, and other similar scientific and biotech lab equipment
Provide technical support for the installation, evaluation and ongoing support of new instruments, including establishing recalibration & maintenance frequencies
Respond to automation-based work requests, log and manage all work in JIRA (or other ticketing system as appropriate) and provide regular reports as requested by the Supervisor
Maintain clear communication and high levels of customer service with appropriate JBEI and ABF personnel concerning service and support issues, including instrumentation and process troubleshooting
Laboratory responsibilities will occasionally include both routine and advanced molecular biological and microbiological work
Follow established SOPs for DNA construct assembly, and DNA sequence validation
Lead efforts to record and report DIVA DNA service costs and labor hours, and to assess researcher compliance with JBEI and ABF publications policies
Contribute to the preparation of scientific and technical manuscripts for peer-reviewed publication and posters for presentation at scientific and technical conferences and meetings
Additional Responsibilities as needed:
Create user interface, analysis, sample tracking and/or process software tools as needed (e.g. LIMS)
What is Required:
B.S. degree in Biology, Engineering or related discipline with 2-3 years minimum professional technical experience in a research laboratory preferred or an equivalent combination of education and experience
Demonstrated experience applying technical, scientific, and engineering principles to evaluate manual laboratory work protocols/process and develop automated work processes
Strong knowledge and expertise in laboratory technology including automated high-throughput and biotech instrumentation, including the ability to create, validate, optimize, and maintain liquid handling processes on robotic workstations
Experience with scripting automated workflows on robotic liquid handlers (e.g., Biomek FXP/NXP/FX/NX)
Knowledge of Visual Basic, VBScript, Biomek, Biomek Method Launcher, and Semi Ex programming for data manipulation & instrument integration
Experience gathering feedback and requirements and analyzing data to make recommendations
Demonstrated knowledge and skills in biology, molecular biology, biochemistry, microbiology, or related field
Excellent interpersonal skills for working in a team environment
Strong written and verbal communication skills
General personal computer application skills with spreadsheets, databases, and word processors
Ability to handle multiple tasks in parallel while working effectively
Good organizational and record keeping skills
Additional Desired Qualifications:
Familiarity with any major programming language (e.g. Python, C#.NET, C/C++)
Familiarity with Coastal Genomics/Hamilton NIMBUS, Labcyte Echo550, and Molecular Devices QPix460 instruments
Experience with advanced modern cloning techniques
The posting shall remain open until the position is filled.
This is a full time, 2 year term appointment with the possibility of extension or conversion to Career appointment based upon satisfactory job performance, continuing availability of funds and ongoing operational needs.
Classification will depend upon the applicant's level of skills, knowledge, and abilities.
M-F, exempt (monthly paid) from overtime pay.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be primarily performed at: Joint BioEnergy Institute (JBEI) -- Bldg. 978, 5885 Hollis St., 4th floor, Emeryville, CA.
Biological Systems and Engineering Division
Vision: To lead efforts that combine the power of biology with the tools of engineering to develop sustainable energy and biomanufacturing solutions and improve human health.
Mission:Advance a mechanistic and predictive understanding of complex biological systems over multiple scales in terms of their responses to manipulation, stress, disease and environmental challenges and translate this knowledge using engineering principles to develop resilient systems, tools, and processes for the efficient production of fuels, chemicals, materials, tissues, and therapeutics.
Berkeley Lab (LBNL) addresses the world's most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab's scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy's Office of Science.
Working at Berkeley Lab has many rewards including a competitive compensation program, excellent health and welfare programs, a retirement program that is second to none, and outstanding development opportunities. To view information about the many rewards that are offered at Berkeley Lab- Click Here.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law.
Lawrence Berkeley National Laboratory encourages applications from women, minorities, veterans, and other underrepresented groups presently considering scientific research careers.
Internal Number: 90195
About Lawrence Berkeley National Laboratory
In the world of science, Lawrence Berkeley National Laboratory (Berkeley Lab) is synonymous with excellence. Thirteen scientists associated with Berkeley Lab have won the Nobel Prize. Fifty-seven Lab scientists are members of the National Academy of Sciences (NAS), one of the highest honors for a scientist in the United States. Thirteen of our scientists have won the National Medal of Science, our nation's highest award for lifetime achievement in fields of scientific research. Eighteen of our engineers have been elected to the National Academy of Engineering, and three of our scientists have been elected into the Institute of Medicine. In addition, Berkeley Lab has trained thousands of university science and engineering students who are advancing technological innovations across the nation and around the world. Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular... views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2011 is $735 million, with an additional $101 million in funding from the American Recovery and Reinvestment Act, for a total of $836 million. A recent study estimates the Laboratory's overall economic impact through direct, indirect and induced spending on the nine counties that make up the San Francisco Bay Area to be nearly $700 million annually. The Lab was also responsible for creating 5,600 jobs locally and 12,000 nationally. The overall economic impact on the national economy is estimated at $1.6 billion a year. Technologies developed at Berkeley Lab have generated billions of dollars in revenues, and thousands of jobs. Savings as a result of Berkeley Lab developments in lighting and windows, and other energy-efficient technologies, have also been in the billions of dollars. Berkeley Lab was founded in 1931 by Ernest Orlando Lawrence, a UC Berkeley physicist who won the 1939 Nobel Prize in physics for his invention of the cyclotron, a circular particle accelerator that opened the door to high-energy physics. It was Lawrence's belief that scientific research is best done through teams of individuals with different fields of expertise, working together. His teamwork concept is a Berkeley Lab legacy that continues today.