Seeking a Research Assistant to work in the Department of Pediatrics Neuroscience section in a lab setting.
We are looking for a Research Assistant 1 to join our research team who is about to complete their undergraduate degree or is a recent graduate. Ideally, this position should allow the candidate to launch a career in biomedical sciences as a physician scientist, a biomedical researcher, etc. We study the role of the Extracellular Matrix (ECM) in regulating glial cells during injury to the developing brain using in-vivo and in-vitro rodent model systems. Insights gained from this work will provide strategies to promote repair and regeneration of the brain from injuries sustained for example during premature birth, childhood stroke, traumatic brain injury, etc. This NIH-funded study will define mechanisms of myelination failure and the cellular targets of injury in WM lesions with a focus on the role of astrocytes and glial scar formation in myelination failure involving arrested maturation of oligodendrocyte progenitors. A central focus is the role of the ECM molecule hyaluronic acid, which we have shown to play a role in myelination failure (see: Nature Medicine 11:966-972, 2005; Preston et al., Annals of Neurology73:266-280, 2013; Srivastava et al., Journal of Clinical Investigation , 128 : 2025-2041 , 2018.
The applicant will have a chance to learn the techniques that we routinely use like animal surgery, tissue sectioning/staining for quantitative analysis, western blotting, primary cell culture, etc. depending on the demands of the project underway in the lab. Responsibilities include assist in designing and conducting experiments, data analysis, record-keeping and data presentation. Attend weekly lab meetings and present your research.
Bachelor degree with no experience OR Associates degree with 2 years of relevant experience OR No degree with 4 years relevant research experience.
The applicant should have familiarity with basic Molecular Biology techniques (PCR, RT-PCR) and/or basic Microscopy.
The applicant should be comfortable handling rodents (neonatal and adult).
MD and/or PhD
Coursework taken pertaining to Neurobiology/Neuroscience or Physiology.
Experience in advanced molecular biology, biochemistry techniques.
Excellent organizational and communication skills, be enthusiastic about their work, and be highly motivated to succeed in a multi-disciplinary/multi-collaborator setting that provides a wealth of opportunities in one of the major universities for neuroscience research in the U.S.
Familiarity with any one or all of the following:
cell culture techniques handling fixed/frozen tissue sections for immunohistochemistry
Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or firstname.lastname@example.org.
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