Research - Laboratory/Non-Laboratory, Staff/Administrative
UCSD Layoff from Career Appointment: Apply by 03/24/2020 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor.
Special Selection Applicants: Apply by 04/02/2020. Eligible Special Selection clients should contact their Disability Counselor for assistance.
The UCSD Department of Cellular and Molecular Medicine (CMM) is one of two basic science units in the School of Medicine where world-class researchers study fundamental cellular processes and pathways using a variety of techniques from classical genetics and fluorescence microscopy to high- throughput genomics, systems biology, and crystallography. Our 36 faculty and over 200 postdoctoral scholars, graduate students, and research staff work on the cutting edge of biology, cutting across fields from basic biochemistry and genetics to genomics, systems biology and stem cell biology.
The faculty also play a major role in medical and graduate student training, providing educational and programmatic offerings that span several disciplines and provide diversity to meet the interests of a broad spectrum of students and scholars. We constantly seek to recruit highly motivated, technologically-advanced, and deeply interested individuals who are ready to become a part of our dynamic research and educational environment.
Under supervision, perform entry level research associate duties in a lab that uses combination of biochemistry and structural biology (both x-ray crystallography and cryo-electron microscopy) to study genome organization in mitosis and meiosis, and bacterial innate immunity mechanisms.
The incumbent will pursue specific projects involving molecular biology (cloning protein-coding sequences into vectors for bacterial expression, using restriction enzymes and/or isothermal assembly), protein purification (expression in E. coli, cell lysis, and liquid chromatography, and biochemistry (including characterization of protein complex assembly and molecular weight by size-exclusion chromatography, measurement of DNA-binding or peptide binding by fluorescence or gel-shift methods, and measurement of ATPase activity using spectrophotometric assays). Duties will also include lab organization and maintenance, moderate administrative work including ordering, safety oversight and supervision of undergraduate lab assistants.
Theoretical and practical knowledge of biochemistry, molecular biology, structural biology, including relevant laboratory techniques.
Demonstrated experience in general laboratory equipment including spectrophotometers, centrifuges, balances, autoclaves, and pH meters.
Excellent organizational and record-keeping skills. Ability to follow and troubleshoot established lab protocols and procedures.
Proven interpersonal, oral, and written communication skills. Ability in using tact, diplomacy, discretion, and flexibility with diverse personalities and situations.
Proven ability to work as part of a research team and interact effectively with collaborating labs and others in scientific community, maintaining good working relationships with all members of the research group.
Knowledge to proactively maintain an organized lab and stocks of essential supplies and media, purchase new equipment, and ensure lab equipment is operating effectively.
Proficient skill and knowledge with computers word processing, spreadsheet, and internet programs.
Solid knowledge of proper handling, storage, and disposal of chemicals, biochemicals, hazardous chemicals, and biohazardous materials including radioactive materials. Knowledge of Material Safety Data Sheets.
Prior experience working in a lab that focuses research on biochemistry and structural biology (both x-ray crystallography and cryo-em microscopy).
Employment is subject to a criminal background check.
Occasional evenings and weekends may be required.
Must be willing to work with hazardous materials.
Must be able to vary work schedule to accommodate research needs.
UC San Diego is an academic powerhouse and economic engine, recognized as one of the top 8 public universities by U.S. News and World Report. Innovation is central to who we are and what we do. Here, students learn that knowledge isn't just acquired in the classroom - life is their laboratory. UC San Diego's rich academic portfolio includes six undergraduate colleges, five academic divisions and five graduate and professional schools. The university's award-winning scholars are experts at the forefront of their fields with an impressive track record for achieving scientific, medical and technological breakthroughs.