Research - Laboratory/Non-Laboratory, Staff/Administrative
A Researcher 2 is wanted to work with a translational research group that is focused on studying novel targeted and immune based treatment approaches for cancer, with a particular focus on blood cancers. The primary responsibilities include working with the supervisor and other members of a collaborative translational research team to carry out complex, multi-step lab techniques, compile and interpret results, and aid with the presentation and publication of the findings. The position involves working with a variety of experimental techniques that incorporate clinically-relevant in vitro and in vivo human and mouse cancer models including patient-derived xenografts. The major focus of our work is to evaluate novel cancer treatment approaches that combine inhibitors of cancer signaling and cell-based immunotherapy to provide the foundation for human clinical trials for patients at the University of Minnesota. Experience with sterile cell culture techniques, multiparameter flow cytometry, Western blotting, molecular cloning, genetic engineering, and mouse models are preferred. Dependability, integrity, and strong communication and interpersonal skills are required. This position involves working closely with a large translational research group along side physician scientists, post-docs, graduate students, undergraduate students, and other lab staff.
Job Duties/Responsibilities 90% - Lab Based Research Lab-based research while working with supervisor, includes planning experiments and independently performing simultaneous complex experiments including: -working with experimental mice -cell culture based assays -multiparameter flow cytometry assays -assisting with experiments -conduct review of relevant literature
5% - General Lab Maintenance Duties include oversight of inventory, maintaining protocols, and ordering of supplies Must maintain a detailed lab notebook that will be reviewed regularly with PI for record keeping and replicating experiments Assisting with compiling data, interpretation of results, and writing manuscripts Generate publication quality figures for presentation and/or publication Attend meetings with supervisor and lab meetings
5% - Supervision Supervision of other lab members
All required qualifications must be documented on application materials.
Required Qualifications 1. A bachelor's degree in the biologic sciences with at least 1 year of related experience OR a combination of education and experience to equal 5 years with coursework related to molecular & cellular biology, cancer biology, and genetics 2. Previous experience working in a laboratory setting 3. Ability to self-motivate and work independently 4. Ability to follow detailed protocols and standard operating procedures 5. Willingness to learn and develop new techniques and approaches 6. Excellent organization skills and strong record keeping abilities 7. Strong interpersonal skills including excellent written and verbal communication skills 8. Proficient computer skills using MS Word, Excel, PowerPoint
Preferred Qualifications 1. Previous experience performing some or all of the following: - in vitro sterile cell culture - multiparameter flow cytometry, including analysis - mouse work in specific pathogen free (SPF) environment, perform injections and necropsies - plasmid and viral-based genetic engineering, isolation of protein/DNA/RNA, immunoblotting, PCR, molecular cloning 2. Demonstrated experience conducting complex multi-step cell and molecular biology experiments 3. Familiarity with Prism Graph Pad
Internal Number: 335390
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.