Research - Laboratory/Non-Laboratory, Staff/Administrative
Postdoctoral Research Associate
University of Notre Dame
The University of Notre Dame (ND.jobs) is accepting applications for a Postdoctoral Research Associate.
Applications will be accepted until 2/9/2020.
The goal of Dr. Xin Lu's lab (https://biology.nd.edu/labs/lu-lab/) is to identify novel therapeutic targets and realize innovative combination therapy strategies to benefit cancer patients, through mechanistic investigation, functional genomics, mouse modeling and therapeutics development (most recent publications: Wang*, Lu*, et al. Cancer Discovery, 2016; Lu et al. Nature, 2017; FengLu, PNAS 2018). Located at the Department of Biological Sciences at the University of Notre Dame and affiliated with Indiana University Simon Cancer Center, the Lu lab is seeking highly motivated Ph.D. candidates with expertise and interests in one or more of following areas:
Cellular, biochemical or metabolic mechanism of cancer progression and metastasis, especially for but not limited to prostate cancer and breast cancer
Tumor microenvironment, tumor immunology and/or cancer immunotherapy (including combination immunotherapy)
Computational cancer bioinformatics, integrated analysis of oncogenomics and/or proteomics data and functional validation in cell culture and animal models. A range of possible project topics includes: (1) Mechanistic understanding of immunosuppressive myeloid cells; (2) Metabolic reprogramming to enhance cancer immunotherapy; (3) Molecular mechanism of prostate or breast cancer metastasis; (4) Anti-metastasis and pro-metastasis functions of neutrophil subsets in cancer; (5) Gene identification and therapy development to treat lethal prostate cancer or breast cancer; (6) Novel mouse modeling and mechanistic understanding of rare cancers, especially VHL disease.
Minimum Qualifications: A doctoral degree in molecular biology, biochemistry, cell biology, immunology, bioinformatics or related field is required. A qualified candidate should hold or expected to hold (within ~ 6 months) a doctoral degree at the time of applying.
Preferred Qualifications: Experience in mammalian cell culture, basic molecular cloning, cell biology, biochemistry or bioinformatics is required. Experience in RNAi, CRISPR, cancer biology, immunology, animal models, histopathology, and/or computational biology is highly desirable, but not required. Furthermore, a notable publication record, strong interpersonal and teamwork skills are also required.
ABOUT NOTRE DAME: The University of Notre Dame, founded in 1842 by Rev. Edward F. Sorin, C.S.C., of the Congregation of Holy Cross, is an independent, national Catholic university located in Notre Dame, Ind. For the fifth consecutive year, the University of Notre Dame has received Honor Roll distinctions as one of the top 10 higher education workplaces in the country in the Chronicle of Higher Education's annual 'Great Colleges to Work For' survey...and we are proud of it!
This appointment is contingent upon the successful completion of a background check. Applicants will be asked to identify all felony convictions and/or pending felony charges. Felony convictions do not automatically bar an individual from employment. Each case will be examined separately to determine the appropriateness of employment in the particular position. Failure to be forthcoming or dishonesty with respect to felony disclosures can result in the disqualification of a candidate. The full procedure can be viewed at https://facultyhandbook.nd.edu/?id=link-73597.
Equal Opportunity Employment StatementThe University of Notre Dame seeks to attract, develop, and retain the highest quality faculty, staff and administration. The University is an Equal Opportunity Employer, and is committed to building a culturally diverse workplace. We strongly encourage applications from female and minority candidates and those candidates attracted to a university with a Catholic identity. Moreover, Notre Dame prohibits discrimination against veterans or disabled qualified individuals, and requires affirmative action by covered contractors to employ and advance veterans and qualified individuals with disabilities in compliance with 41 CFR 60-741.5(a) and 41 CFR 60-300.5(a).
APPLICATION PROCESS: Please apply online at http://ND.jobs to Job # S20028. For additional information about working at the University of Notre Dame and various benefits available to employees, please visit http://hr.nd.edu/why-nd. The University of Notre Dame supports the needs of dual career couples and has a Dual Career Assistance Program in place to assist relocating spouses and significant others with their job search.
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