New postdoctoral positions are available in the laboratory of Dr Micheala Aldred in the Pulmonary Division of the Department of Medicine. We study the genetic basis of pulmonary arterial hypertension (PAH), a serious lung vascular disorder, utilizing state-of-the-art genomic and epigenomic technologies to understand the molecular changes that contribute to this disease. Major NIH-funded projects in the lab focus on the role of DNA damage in the pathogenesis of PAH and therapeutic approaches to correct bone morphogenetic protein signaling in the heritable form of the disease (Federici et al., Am J Respir Crit Care Med, 2015, 192: 219-228; Drake et al., Am J Respir Cell Mol Biol, 2013, 49: 403-409).
Applicants should have a recent PhD or MD/PhD degree in genetics or molecular biology, excellent communication skills and a strong track record of first-author publications. Expertise in mammalian genetics or DNA damage pathways is essential. Additional training in bioinformatics, analysis of next-generation sequence data, and/or animal models of pulmonary hypertension would be highly desirable.
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