As a Biomedical Scientist (Quantitative Proteomics Lead), you will independently design, conduct, analyze, and report studies outlined by your supervisor or Executive Director, and actively propose new avenues of investigation. This exciting position will give you the opportunity to explore novel technology and workflows for process improvement while proactively assigning projects, leads, and writing standard operating procedures (SOPs). You will guide a small team dedicated to developing quantitative proteomic profiling and targeted assays using both high and low resolution techniques, all while working within a brand-new laboratory equipped with state-of-the-art LC-MS/MS instrumentation (Orbitrap Lumos Fusion, Exploris, QTRAP6500).
Additional Duties and Responsibilities:
Performs hands-on experimental work; must have a thorough understanding of laboratory and research functions.
Manages assigned projects including associate's activities in a regulated working environment.
Leads development of state-of-the-art quantitative proteomics workflows from sample preparation to data analysis.
Performs tasks related to analytical projects, assigns work, monitors progress, and evaluates experimental data. Identifies any issues/problems and makes plans to resolve them.
Prepares written and verbal updates on research findings, including project plans and deliverables.
Practices proper documentation skills, ensuring all documentation complies with Federal and State accrediting agency requirements including CAP/CLIA, ISO, and FDA requirements as necessary.
Writes and reveiws SOPs and maintains computer database of established protocols.
Maintains electronic and non-electronic records under accepted regulatory practices.
Ensures all activities comply with regulatory guidelines and safety standards by monitoring all on-going activities and interacts with other teams within the organization regularly.
Coordinates and assists quality control team with all testing activities where required.
Teamwork/Customer Relations Responsibilities:
Identifies and responds appropriately to customer needs utilizing available resources.
Collaborates to problem solve and make decisions to achieve desired outcomes.
Establishes effective working relationships with cross-functional team(s).
Responds timely, effectively, and appropriately to deliverables.
Shares knowledge, time, and expertise to assist other members of the team.
Team Lead/Supervisory/Management Responsibilities:
Leads projects, trains, and assists other associates on day-to-day lab operations and procedures.
Supervises the day-to-day work of employees, ensures tasks are completed and deadlines are met.
Manages and mentors junior scientists and research technologists.
Responsible for hiring, onboarding, personnel actions, performance reviews, and performance improvement plans.
Department-Specific Responsibilities and Requirements:
Develops of state-of-the-art proteomic workflows and technology.
Experience across the entire proteomic workflow from sample prep to data analysis.
Hands-on experience with Thermo and Sciex mass spectrometry platforms for both low and high resolution analysis techniques.
In-depth knowledge of protein chemistry and allied techniques (electrophoresis, western blot, affinity chromatography).
Familiarity with mass spectrometry analysis software (vendor specific and open source).
These statements describe the primary duties and responsibilities of the job and are not intended to be an exhaustive list of all tasks. Other work duties may be assigned at any time with or without notice.
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research... and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major teaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.