Assistant Project Scientist University of California, Los Angeles
Requisition Number: JPF04988 Recruitment Period Open date: September 16th, 2019 Next review date: Thursday, Oct 17, 2019 at 11:59pm (Pacific Time) Apply by this date to ensure full consideration by the committee. Final date: Thursday, Oct 17, 2019 at 11:59pm (Pacific Time) Applications will continue to be accepted until this date, but those received after the review date will only be considered if the position has not yet been filled.
The Assistant Project Scientist in Dr. Jay Lee Moon's lab will perform independent research to study the immunology of lung cancer (adenocarcinoma). He/She will also be responsible for supervising graduate students and undergraduate student researchers, preparing manuscripts for publication in scientific journals, writing grants and assisting with the preparation of grant proposal and annual reports. The Assistant Project Scientist will also conduct preclinical studies in animal models. The responsibilities include coordinating the purchase, receipt maintenance, and transfer of mice with DLAM staff, and use the mice in research project and to support the endeavors of the research team. This position requires a Ph.D in Biotechnology and a minimum of 5 years of experience in cell signaling in lung disease. The Assistant Project Scientist position is a 12 month, non-senate position.
Specific Responsibilities include: The assigned project is focused on discovering the mechanisms involved in immunology of lung diseases, specifically to understand the molecular signals affecting immune-oncology targets to alter the susceptibility of premalignant cells to checkpoint inhibitors. The principle objective is to find the molecular mechanism behind the resistance development to make immunotherapy more effective. Utilizing the in vitro human premalignant cell culture model and also using in vivo transgenic mice model Kras, Kras;LKB (KL), the objective is to decipher the signaling mechanisms in regulating PDL1 expression during premalignant stage and its subsequent progression to tumor. This involves molecular and immunologic approaches, in vitro/in vivo assays, ELISA, Westernblots, qPCR, microscopy, cell culture. Responsibility of this position include study design, executing in vitro studies and in vivo studies, literature review and manuscript/grant preparation.
Additional Duties: Successful grant writing and grant submission; Supervision of undergraduates, graduate students and new postdoctoral trainees in the lab; Lab Managing and safety management; Ability to work on multiple projects simultaneously, efficiently and effectively; Ability to work with regulatory agencies and insure lab procedure, equipment and space compliance; Ability to work independently on scientific projects; Assist with preparation of grant proposals; Preparation of manuscripts for publication in scientific journals; Required to communicate well with scientist's worldwide; Candidates should have 5 years research experience in lung biology and immunotherapy in an academic setting or equivalent; Candidate should have extensive experience in lung cancer; Candidate should have excellent publications (in high impact journals); The candidate will report directly to the Principal Investigator and will successfully carry out experiments and analyze the data generated with minimal supervision; Ability to help and train various personnel in molecular biology and immunology and make significant contribution to the design and execution of other laboratory member's experiments.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy.
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy, https://policy.ucop.edu/doc/4000376/DiscHarassAffirmAction
UCLA is known worldwide for the breadth and quality of its academic, research, health care, cultural, continuing education and athletic programs. UCLA offers undergraduate degrees in more than 127 majors and graduate degrees in 198 program areas. UCLA has 11 highly regarded professional schools. Eight are ranked among the nation's top 15 in their field by U.S. News & World Report. UCLA is consistently among the most popular campus in the nation for undergraduate applicants. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, national origin, disability, or protected veteran status. Benefits:UCLA offers a comprehensive benefits package, including an average of three weeks' vacation per year; an average of 12 days per year sick leave; 13 paid holidays per year; health, dental and optical benefits; life insurance; disability insurance; the University of California Retirement Plan with 5 year vesting and various voluntary UC Savings Plans. There are also special programs and privileges available, such as accessibility to cultural and recreational programs, athletic events, and the University Credit Union.