Job Summary/Essential Job Functions: Under the direction of an assigned supervisor, this position exists to study the role of exosomal cytochrome P450 enzymes and underlying mechanisms in alcohol and tobacco/nicotine-mediated oxidative stress, response to antiretroviral drugs, cytotoxicity, and HIV-1 replication, and their implications on HIV-1 pathogenesis and neuroAIDS. The position also exists to expand the current research areas into interaction of HIV with other comorbidities and coinfections such as cancer and Alzheimer's disease.
DUTIES AND RESPONSIBILITIES:
Confers with principal investigator regarding the experimental design and application.
Proposes and designs experiments.
Performs molecular and cell biology experiments.
Maintains cell lines and primary cells; and runs PCR, RTPCR, Western Blot, Flow cytometry.
Performs various oxidative stress experiments.
Treats cells with various agents (alcohol, tobacco) and isolates DNA, RNA, and protein.
Assists with researching and completing new grant applications.
Writes publications on research carried out in the laboratory.
Sets relative priority of experiments to be run and bring forth budgeting issues for material to be ordered.
Interacts with lab members to coordinate research efforts for increased efficiency.
Performs other related duties as assigned.
Internal Number: 184606
The mission of the University of Tennessee Health Science Center is to bring the benefits of the health sciences to the achievement and maintenance of human health, with a focus on the citizens of Tennessee and the region, by pursuing an integrated program of education, research, clinical care, and public service.