This position is full-time and works approximately 40 hours per week.
Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
Applicants should have a PhD or MD and demonstrated relevant research experience and publication record.
Excellent verbal and written communication skills are essential.
A strong background in either hematopoiesis / immunology, developmental biology, or cell biology is preferred, but not required.
Previous bioinformatics or murine xenograft assay experience would be an asset.
Post Doc Instructions:
Please do not submit an application to this posting.� To apply for this postdoctoral research opportunity, follow the directions below in �Applicant Special Instructions�.
Interested applicants should send a current CV, statement of research interests, and 2-3 contacts for reference letters, to Dr. Christopher Sturgeon (email@example.com).
Department Name/Job Location:
This position is in the Department of Internal Medicine, Division of Hematology. This position is for the Medical School Campus.
Postdoctoral Research Position: Pluripotent Stem Cell Differentiation and Regenerative Medicine
A postdoctoral research position is available in the laboratory of Dr. Christopher Sturgeon, at the Washington University School of Medicine, in St. Louis, MO. We have developed novel human pluripotent stem cell (hPSC) directed differentiation strategies that generate extra-embryonic and intra-embryonic like hematopoietic progenitors. Several research projects are available, all focused on the translational potential of these hPSC-derived hematopoietic stem/progenitor cells. Possible projects range from the development of hPSC-derived adoptive immunotherapies, epigenetic and post-transcriptional regulation of hematopoietic development, and the characterization of engraftable hematopoietic populations.
The applicant will be responsible for managing their own projects as well as collaborating both within the Sturgeon laboratory, and with other local groups.
Sturgeon CM, Ditadi A, Awong G, Kennedy M, Keller G. Wnt Signaling Controls the Specification of Definitive and Primitive Hematopoiesis From Human Pluripotent Stem Cells. Nature Biotechnology. 2014 32(6):554-561
Ditadi A, Sturgeon CM, Tober J, Awong G, Kennedy M, Phillips A, Ng ES, Stanley E, French DL, Cheng X, Gadue P, Speck N, Elefant AG, Keller G. Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages. Nature Cell Biology. 2015 17(5):580-591
Creamer JP, Dege C, Ren Q, Ho JTK, Valentine MC, Druley TE, Sturgeon CM*. Human definitive hematopoietic specification from pluripotent stem cells is regulated by mesodermal expression of CDX4. Blood. 2017 129(22):2988-2992.
Fok WC, Niero ELO, Dege C, Brenner KA, Sturgeon CM*, Batista LFZ*. p53 mediates failure of definitive hematopoiesis in dyskeratosis congenita. Stem Cell Reports. 2017 9(2):409-418
Ditadi A, Sturgeon CM, Keller G. A view of haematopoietic development from the Petri dish. Nature Reviews Molecular Cellular Biology. 2017 18(1):56-67
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.