The Danino laboratory (http://daninolab.nyc) within the Department of Biomedical Engineering is currently welcoming applications for a Research Assistant.
Reporting to the lab director Dr. Tal Danino, the incumbent is responsible for a broad range of research activities and other related duties in the Danino lab. The lab focuses on using Synthetic Biology to engineer bacteria to treat cancer. We perform molecular cloning to construct therapeutic bacteria in vitro, and then work with various in vitro and animal models of cancer to test our bacteria. This position is specifically posted to assess therapeutic bacteria in animal models.
This is a grant-funded position and continuation is subject to funding.
Run multiple projects in parallel, in collaboration with PhD students and postdocs, maintain a clear, organized, up to date notebook and interact well with their supervisor and others in the laboratory.
Work closely with other labs at CUIMC
Performs other tasks, duties, and responsibilities as required
Education: bachelor's degree in scientific, engineering, or medical field
Experience: One year experience working with animal and cancer models.
Skills and Knowledge:
1. General molecular biology techniques including bacteria and cell culture.
2. The ability to work independently, under minimal supervision, following appropriate training
3. Knowledge of basic chemical and/or biological terminology and techniques
4. Ability to research literature applicable to the field
5. Ability to present experimental data to lab members and the Principal Investigator
6. Ability to perform work in a neat and orderly manner in accordance with safety regulations
7. Computer literacy: proficiency with Microsoft Office and other graphical and data analysis software
8. Excellent motivation, interpersonal, communication and organizational skills
Experience: Previous full-time experience as a research technician
Skills and Knowledge:
Animal studies: Cancer models, subcutaneous/intravenous/intraperitoneal injections, surgical techniques, anesthesia, IVIS imaging, mouse colony management. Activation of primary mouse immune cells from lymphoid and non-lymphoid tissues, including lymph nodes, spleen, lung, intestines, liver, adipose tissue and skin;
Tissue culture: Sterile technique, passaging and maintenance of cells lines and primary cells, media preparation, cryopreservation
Molecular biology techniques: restriction digest, PCR, quantitative PCR, cloning, gel electrophoresis, mutagenesis, Gibson assembly, etc.
Technology: Familiar with microscopy, flow-cytometry
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 502045
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