Research - Laboratory/Non-Laboratory, Staff/Administrative
Department: Human Sciences Administration
Summary of Duties:
The College of Education and Human Ecology (EHE) at The Ohio State University is looking for a Postdoctoral Researcher to support the Health and Nutritional Metabolomics Lab within the Department of Human Science!
The College of Education and Human Ecology values learning as a lifelong process. The educators, researchers and professionals we help grow are critical to shaping academic success and health and wellness for generations to come. EHE embodies the mission and goals of OSU, and is committed to:
Creating and discovering knowledge to improve the well-being of our state, regional, national and global communities;
Educating students through a comprehensive array of distinguished academic programs;
Preparing a diverse student body to be leaders and engaged citizens;
Fostering a culture of engagement and service;
Understanding that diversity and inclusion are essential components of our excellence. We are led by our core values of excellence; diversity in people and of ideas; inclusion; access and affordability; innovation; collaboration and multidisciplinary endeavor; and integrity, transparency and trust.
About the Department of Human Sciences
Our work in the Department of Human Sciences brings together theory and practice to share and improve the community in powerful ways. Our centers and programs develop and execute innovative strategies that improve educational and healthy living opportunities for children, adults and families in cities, states and nations around the world. The College of Education and Human Ecology at The Ohio State University is one of the best places to learn and embrace the human experience. We’re known for developing Ohio’s best educators, researchers, policymakers, exercise scientists, dietitians, financial advisors, event coordinators and other experts who improve society, and we are one of the most highly regarded colleges in the United States for research, teaching and community engagement that changes the world.
The Post-Doctoral Researcher will utilize mass spectrometry to identify biomarkers and therapeutic targets by `Omics’ approaches. The successful candidate will perform metabolomic analysis and combine results with systems biology approaches in animal models and humans to identify diagnostic and therapeutic biomarkers for metabolic and cancer diseases. This opportunity will also perform targeted quantitative metabolomics analysis of urine, feces, plasma and tissue samples from cell culture, mouse and human samples using GC-MS and LC-MS. Further, the incumbent will develop and perform metabolic flux studies in animal and cell culture models. The Post-Doctoral Research will play a pivotal role in all phases of the research cycle including experimental design, sample preparation and analysis, data analysis and interpretation as well as manuscript preparation. The role will actively engage in method development and validation, reviews of appropriate literature, and supporting the PI through managing multiple projects as well as providing trouble-shooting assistance within the laboratory. The idea candidate is self-motivated, takes initiative, and works will with a variety of personalities and skills levels.
This role will work within the Health and Nutritional Metabolomics Lab directed by Dr. Chris Zhu, Assistant Professor in the Department of Human Sciences and Member of the Comprehensive Cancer Center at The Ohio State University, in Columbus, Ohio. The Zhu laboratory uses targeted/untargeted metabolomics and ambient mass spectrometry along with in vitro model systems, animal models, cell culture studies, and clinical studies to integrate basic research into translational nutrition and medicine. This is a one year Term position with the potential to be renewed for additional year(s) based on performance and funding availability.
In the first 60 to 90 days of employment, the successful candidate for this position will accomplish the following: -Develop a comprehensive understanding of college and university policies and procedures -Establish pivotal relationships within the college and across the university's research laboratory operations -Conduct a review of current laboratory processes and support the development of research programs for the laboratory A long-term goal of this position is to accurately and consistently perform metabolomics analysis to inform research in the areas of metabolic and cancer diseases.
Additional Information for Applicants::
Please attach CV including education background, publication list and at least three names and email addresses of references. Additionally, please submit a summary of previous and current research and future plan (1-2 pages) in the Cover Letter or Other document attachments within the application.
The selected candidate for this position will have demonstrated success in several areas, including:
Ph.D. in Analytical chemistry, Chemistry, Biochemistry or Life Sciences
Strong background and hands-on experience in qualitative and/or quantitative mass spectrometry
Experience developing and performing metabolic flux assays required
Hands-on experience in GC-MS, LC-MS and HPLC, preferably in small molecule analyses
Experience in MRM method development
Experience in handling bacterial culture, tissue culture and mouse models
Strong analytical background and excellent problem-solving skills
Desired requirements include:
Experience in colon cancer or metabolic disease research areas
Prior experience with microbiology and microbiome studies are highly desired
Target Salary: $48,000.00 - $48,000.00 Annually
Job Category: Research
Job Appointment (FTE%):
The Ohio State University is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation or identity, national origin, disability status, and protected veteran status.
The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. Founded in 1870, Ohio State is a world-class public research university and the leading comprehensive teaching and research institution in the state of Ohio. With more than 63,000 students (including 57,000 in Columbus), the Wexner Medical Center, 14 colleges, 80 centers and 175 majors, the university offers its students tremendous breadth and depth of opportunity in the liberal arts, the sciences and the professions.