This positioninvolves work in a team environment to support proteomic discovery effortsleveraging quantitative mass spectrometry for cancer biomarker identificationand validation. Areas of focus willinclude analyzing mass spectrometry datasets collected using DDA(data-dependent acquisition, both label-free and with labeling strategies) tointerrogate changes in relative protein levels, as well as those aimed to assesschanges in post-translational modification status. To this end, the successful candidate willhave access to substantial computational resources including a high performanceenvironment with 10,000 cores and GPUS. The successful candidate will updateand document advanced mass spectrometry data analytics processes and track how theseanalytic methods are applied for various projects. There will be ample research opportunitiesacross a broad variety of projects both within CEDAR and with external partners- you will collaboratively engage with experimentalists, other computationalbiologists, and clinicians in the CEDAR team-oriented environment to support advancedanalytic capabilities for a variety of projects leveraging mass spectrometry-basedproteomics. Areas of particular focusfor this position include statistical association of proteomic outputs withclinical metadata and/or experimental sample state changes, workflowdevelopment for handling proteomic MS data acquired using new data acquisitionstrategies and/or from new instrument formats, and integration of proteomicsdatasets with other complementary data types for multi-omic studies.
As the state's only health and research university, OHSU brings together patient care, research, education of the next generation of health care providers and scientists and community service to improve the health and well-being of all Oregonians.The university is a conduit for learning for more than 2,800 students, providing training to interns, residents and fellows in postgraduate medical and research. It is the only place in Oregon that grants doctoral degrees in medicine, dentistry and nursing. OHSU cares for more than 251,000 patients each year from around the region and takes a leadership role in contributing to solutions involving the health of the state and the nation, such as health care access and transparency, ethics and workforce shortage. Beyond providing critical health care services, quality education and cutting-edge research, OHSU also is a key economic and social force in the Northwest. With an annual operating budget of $2.06 billion and more than 14,000 employees, OHSU is Portland?s largest employer. Its size contributes to its ability to provide... many services and community support activities not found anywhere else in Oregon. For more information visit http://www.ohsu.edu/xd/about/index.cfm