Research Technician - Immunology, School of Medicine - (19001490)
The Department of Immunology maintains research programs that focus on translational and basic research in areas relevant to human disease. The strength of the department lies with an integrated faculty interested in understanding how immunological, physiological and metabolic pathways interact to produce dysregulated, innate and adaptive host responses in a wide array of chronic diseases. These include autoimmunity, cardiovascular disease, transplantation, infectious diseases, cancer, obesity and diabetes. Our goal is to become a world-class center for the study of inflammation and the targeted development of novel therapeutics for both treatment and prevention of immune-mediated diseases.
The research in our laboratory is focused on understanding the molecular mechanisms controlling the identity and function of regulatory T cells (Tregs) in the settings of autoimmune disease and cancer. The long term goal is to treat autoimmune diseases using Tregs-based cell therapy and to target Tregs in cancer immunotherapy. Major interests include: understanding the molecular underpinning of Treg cellular identity in order to reprogram non-Treg cells into Tregs to treat autoimmune disease; Understanding how Tregs adapt to tissue and immune microenvironments in order to more specifically target them to treat autoimmune disease and cancer. This is a position in a highly focused and collaborative research group, and we seek a motivated individual who is enthusiastic to learn and work with the group on questions related to this research focus. Under supervision of the Principal Investigator and experienced graduate students, the Research Technician will conduct a variety of experiments following established procedures/protocols, which may include bacterial and mammalian cell culture, retroviral vector production, flow cytometry, PCR and electrophoresis, DNA and RNA extraction and characterization, mouse models of autoimmune diseases, and other laboratory techniques. In these capacities, the Technician will also record test results and analyze data. In addition, the Technician will assist in managing mice colonies, monitoring the proper functioning of laboratory equipment, and organizing and maintaining logbooks and supplies.
Bachelor's degree in science with up to 1 year laboratory experience.
Bachelor's degree in Biology, Biochemistry, Microbiology/Immunology, or related fields.
Proficient in using Microsoft Office products.
Must be able to fluently communicate, read, and write in the English language.
Self-motivation, consistent attention to detail, and excellent organizational, communication, and time management skills are critical.
Previous experience using molecular biology, cell biology, and immunology techniques is highly preferred.
Previous experience working with mice as a research model is preferred but not required, although willingness to be trained to work with mice is necessary.
Special Work Schedule Requirements: Occasional need to work overtime, holidays, or weekends when required by certain experiments.
An employee in this position must complete all appropriate background checks at the time of hire, promotion, or transfer.
Primary Location: United States-Massachusetts-Boston
Organization: Department of Immunology
Employee Status: Regular Schedule: Full-time
Job Posting: Jun 17, 2019, 5:17:33 PM
Internal Number: 19001490
About Tufts University
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