We are looking for a talented scientist who will lead investigations related to extracellular matrix biology and progression of chronic inflammation-associated cancer. The applicant is expected to execute and coordinate independently these research activities as part of a Grand Challenge project recently funded by Cancer Research UK. The applicant will work as part of an international research team involved in various aspects of this large-scale project.
PhD degree with a specialty in cell biology, tumor biology, cell signaling and stromal/epithelial interactions.
Experience with in-vitro disease models including 2D organotypic cultures and heterotypic cultures co-culture systems and 3D organoid cultures.
Experience with cell signaling pathway discovery and analysis.
Extensive knowledge of chronic inflammation-associated diseases and cancer development.
Expertise in processing of human tissue specimens including isolation, culture and characterization of primary cells (marker expression analysis, cell function assays (cell permeability assays on transwell))
Expertise in cell biology with an emphasis on cell signaling pathway discovery and analysis; protein biochemistry in particular extracellular matrix isolation and analysis; cancer biology in particular as it pertains to acquisition of cell plasticity phenotypes.
Candidates must meet the qualifications by the time of appointment.
Completion of post-doctoral fellowship.
Track record of independent research.
Extensive knowledge of biological processes involved in progression of chronic inflammation-associated cancers.
Documentation of previous experience in overseeing a project independently with minimal supervision.
Documentation of previous experience as project lead in the context of an international research team.
Senior author on a minimum of 3 peer-reviewed publications relevant to the subject of study.
Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.
UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
Internal Number: JPF02489
About University of California, San Francisco
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.