The Department of Neurosurgery at the University of Minnesota invites applications for a Research Associate position from candidates with a Ph.D or equivalent degree. The laboratory directed by Dr. Clark C. Chen, M.D., Ph.D., is seeking outstanding scientists who are interested in working in a NIH-funded research program studying the role of microglia in glioblastoma pathogenesis.
The Department of Neurosurgery at the University of Minnesota is a well-balanced program with significant achievements in teaching, clinical programs and research. The University of Minnesota is one of the highest ranked public universities in research. The successful applicant will receive training in, and be expected to participate in the design, implementation and evaluation of experiments related to on-going NIH funded research. The University of Minnesota shall provide equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression.
The ideal candidate should have experience in in vitro and in vivo characterizations of EGFRvIII and microglia/macrophages. Required skill sets include: isolation of microglia from murine brain and glioblastoma models, cytokine profiling, and co-culture experiments involving glioblastoma and microglia cells. The candidate should also have experience in the interrogation of The Cancer Genome Atlas (TCGA) dataset as well as training in the handling of clinical tumor specimens and bio-fluids derived from human subjects. The candidate must have the ability to define research questions and develop experiment designs to address those questions. The ideal candidate should have experience with brain tumor research, including primary and metastatic brain tumors. The candidate should have experience presenting research results through publications and presentations.
Principal Duties and responsibilities: • originate research ideas • develop research questions • create research designs • collect data • analyze data • write manuscripts for publications • supervise, as needed, undergraduate, graduate students, junior scientists and postdocs working on related research projects • seek funding opportunities and write grant proposals (e.g. NIH funding)
Minimum qualifications • PhD in biology, biochemistry, molecular biology, cancer biology, or related science field • Expertise in cellular and molecular biology techniques, • Excellent interpersonal skills and ability to work collaboratively with others. • Excellent oral and written communication skills
Preferred qualifications • Experience in studies involving glioblastoma tumor microenvironment • Experience with molecular characterization of Epidermal Growth Factor Receptor variants • Experience in murine intra-cranial tumor models • Experience working multi-color FAC sorting • Experience in bio-informatic analysis of TCGA database • Experience statistical analysis of experimental data • Experience with grant writing • Record of presenting research results through publications and conference abstracts
Internal Number: 329991
About University of Minnesota, Twin Cities
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.