The laboratory of Dr. Emmanuelle Passegué, Director of the Columbia Stem Cell Initiative and Principal Investigator (PI), is seeking an organized and energetic laboratory technician. Dr. Passegué's research team investigates the cellular and molecular processes controlling the activity of blood-forming hematopoietic stem cells (HSC) during homeostasis and addresses how these regulations are altered in myeloid malignancies and physiological aging. The goal of Dr. Passegué's research is to identify affected genes and/or pathways that can be used to develop new therapies to treat human diseases. Towards this end, the Passegué laboratory is employing a variety of cross-disciplinary approaches using primarily genetic mouse models. Current projects investigate the role of apoptosis, autophagy, immune regulations, DNA repair mechanisms, and changes in the bone marrow (BM) niche microenvironment in HSC function in normal and deregulated conditions.
Reporting to the PI and working under the day-to-day direction of the Lab Manager, the Technician will help with the proper running of the laboratory and perform analyses related to a wide range of experiments both in a supervised and independent manner. This is an opportunity for the right candidate to strengthen lab skills as part of a dynamic laboratory team at the forefront of stem cell research.
Perform fully-planned experiments under the direction of senior lab personnel, or conduct independently components of such experiments, which may include areas such as genotyping, flow cytometry, transplantation experiments, cell culture, cell biology, molecular biology, confocal imaging, and histological analyses.
Record and track experimental results accurately.
Assist with management of mouse colonies.
Assist with ordering and maintaining inventory of laboratory supplies, perform assays and prepare solutions adhering to specific instructions, and maintain equipment or specific laboratory resources.
Bachelor's degree in a cell biology, molecular biology, or biochemistry or Bachelor's degree in another field with relevant coursework, laboratory experience, and a demonstrated understanding of the fundamental concepts of biological sciences or a combination of education, training and experience.
Must be detail-focused and organized. Must be able to take instructions and execute assignments working independently, seeking clarification and guidance where needed.
Must demonstrate critical thinking skills and an aptitude for ongoing learning development, especially with regard to complex instrumentation and technology. For someone who demonstrates enthusiasm and aptitude for learning, this position offers the opportunity to strengthen laboratory and research skills, and build new ones.
Excellent interpersonal skills and ability to adapt. Strong communication skills, including the ability to ask questions and provide updates on work progress clearly and with sufficient technical detail.
Solid computer skills.
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 498766
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