At Boston Children's Hospital, success is measured in patients treated, parents comforted and teams taught. It's in discoveries made, processes perfected, and technology advanced. In major medical breakthroughs and small acts of kindness. And in colleagues who have your back and patients who have your heart. As a teaching hospital of Harvard Medical School, our reach is global and our impact is profound. Join our acclaimed Department of Medicine – Genetics and discover how your talents can change lives. Yours included.
Our laboratory is focused on improving the understanding of the underlying genetics of neurodevelopmental disorders and on using genomic tools to develop therapeutics for diseases affecting the central nervous system. We approach genetics questions using a combination of clinical and evolutionary methodologies including the following specific areas. First, development of new methodologies which examine mutations often missed by traditional genetic testing. Second, rigorous large-scale genetic data generation and functional testing of coding and regulatory mutations. Third, evolutionary analysis of coding and noncoding regions regulating human neural development. These approaches inform our translational goal to design and deliver genome-guided therapeutics for seriously ill children.
This Research Assistant I will be responsible for:
Performing a variety of routine laboratory experiments and procedures, utilizing standard laboratory equipment, recording and checking results for completeness and accuracy.
Assisting in troubleshooting procedures if experimental results are unexpected or quality of specimens is poor.
Maintaining records of results and methodologies in a log of work performed.
Maintaining equipment, lab area and supplies in a neat professional manner.
Sterilizing and cleaning glassware, preparing media and other materials using appropriate procedures.
Inventorying supplies alerts supervisor to needed supplies.
Processing order for supplies and/or animals.
Attending courses in safety procedures for handling, storage and disposal of biohazardous, flammable, corrosive and toxic materials. Carries out all laboratory activities in compliance with applicable regulations and protocols.
Conducting literature searches and reviews, compiling information for journals and suggesting uses for new techniques to the P.I. Attends courses, lectures and conferences to further own knowledge of research and laboratory techniques, consulting with other researchers and technicians to exchange information.
Contributing to the team within and between departments and organizations.
Maintaining of C. elegans strains and DNA reagents.
Handling issues with lab equipment, vendors, and departments within Boston Children's Hospital.
Responding to material requests from other groups; and helping lab members in their research.
Carrying out a supervised research project focused on finding out how cells organize themselves into complicated multicellular structures. This project will take advantage of the genetic tools available in C. elegans to determine how proteins are trafficked to different cellular compartments.
To qualify, you must have:
A bachelor's degree in a science.
A molecular and cell biology background.
At least one year research experience.
Strong organizational skills.
Interest in human genetics, specifically related to neurodevelopmental disorders and neurodegenerative diseases.
A strong passion for translational research.
Boston Children's Hospital offers competitive compensation and unmatched benefits.
Boston Children's Hospital is an Equal Opportunity / Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to their race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status or disability.
Internal Number: 2835481
About Boston Children's Hospital
Boston Children's Hospital is a 395-bed comprehensive center for pediatric health care. As one of the largest pediatric medical centers in the United States, Children's offers a complete range of health care services for children from birth through 21 years of age.