Research - Laboratory/Non-Laboratory, Staff/Administrative
Department: MED-Center for Genetic Med Salary/Grade: NEX/12
NUSeq is Northwestern University’s core facility on next-gen sequencing and other state-of-the-art genomics technologies, with the mission to providing infrastructure and expertise on genome research to Northwestern researchers. Located on Northwestern’s Chicago Campus in Streeterville, NUSeq provides 60 services to Northwestern investigators on both Evanston and Chicago campuses. These services cover a broad range of DNA/RNA/genome technologies from automated DNA extraction, DNA/RNA sample QC, cell line authentication, Sanger sequencing, to next-generation sequencing (NGS), microarray, real-time quantitative PCR, and droplet digital PCR.
Recently NUSeq has started a new initiative on clinical NGS to support Northwestern Medicine. This clinical NGS specialist position is created to support this new initiative. The position will cover CLIA/CAP accreditation application, clinical NGS workflow establishment, patient sample processing, and new assay development. The position will have ample support from and interactions with bioinformaticians and pathologists. The Core’s highly collegial team looks to have a new colleague with abundance CLIA NGS experience to launch the Core’s NGS services on clinical and translational research.
Provides daily work oversight and executes research activities. Oversees service workflow in consultation and support of users and junior staff executing procedures. Assists in the development and implementation of new core services, and other core laboratory and research functions. Ensures overall quality of research functions and responsible for unit's compliance in regard to University, sponsor and federal rules and regulations.
Please note, this position may work off normal hours due to delivery of critical clinical samples.
Ensures client billing information is complete and accurate.
Compiles billing information for documenting usage and billing information into the Core's automated service tracking/billing system.
Develops cost analyses on services rendered by the Core.
Assists in preparing cost quotes on experimental design requested by investigators.
Ensures that all work is accurately and completing documented.
Interacts with both Core Staff and clients in the planning and execution of experiments/ core services.
Advises PIs as appropriate.
Ensures compliance with University safety protocols, relative to the use of combustibles, radioactivity, toxic material, and/or carcinogenics.
Maintains sterile conditions as required.
Plans, conducts and evaluates experiments and assays of varying complexity.
Understands, follows, and troubleshoots protocols.
Records, compiles, and reports data
Provides analysis and insightful interpretations of results.
Participates in beta-testing of new protocols and services.
Develops new methods or customizes protocols for users.
Ensures lab is prepared for service delivery (experimentation)
Ensures established inventory levels, and notes usage trends so that inventory levels meet client demand.
Ensures the recommended maintenance on instrumentation and equipment is performed according to manufacturer and University guideline.
Troubleshoots equipment problems, and mitigates the issues with training and/or repair protocols.
Recommends equipment improvements and/or new equipment.
Assists in the development of usage protocols for new equipment.
Ensures compliance with all University, sponsor and federal rules and regulations.
Using an advanced level of skill, completes the following activities (please highlight):
Using a fully functioning level of skill, completes the following activities:
DNA, RNA, isolation, purification and expression
Sequencing of DNA
pH meter, plate reader
Trains or assists in training of technicians and trainees including students.
Provides training to researchers in instrument and equipment operation
Completes other duties as assigned.
Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree; OR appropriate combination of education and experience.
4 years of technical or other relevant experience required.
Minimum Competencies: (Skills, knowledge, and abilities.)
Adequate molecular biology lab skills, including DNA extraction, enzymatic reaction, PCR, sequencing, electrophoresis, etc.;
Good understanding of biochemical properties of nucleic acids and enzymes.
Preferred Qualifications: (Education and experience)
M.S. in a bio-related discipline
Preferred Competencies: (Skills, knowledge, and abilities)
Familiarity with the CAP/CLIA accreditation process.
Skilled in next-gen sequencing technologies, including preparation of libraries, sequencer operation, and run monitoring/troubleshooting.
Experienced in whole genome, exome, and gene panel sequencing of clinical samples.
Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.
Internal Number: 35858
About Northwestern University
Northwestern University is a major private research university with 12 academic divisions located on three campuses in Evanston, Chicago, and Education City in Doha, Qatar. We have approximately 2,500 full-time faculty members, 17,000 graduate and undergraduate students, and over 5,700 full and part-time staff. Northwestern University combines innovative teaching and pioneering research in a highly collaborative environment. It provides students and faculty exceptional opportunities for intellectual, personal and professional growth.