Research Support - Laboratory/Non-Laboratory, Staff/Administrative
Employment Type: Permanent Staff (SHRA)
Vacancy ID: P009838
Salary Range: $61,458 - $69,500
This Synthetic Organic Chemist position will work with UNCHIV Cure Center scientists and faculty and will provide support for the projects of the Center. The Cure Center is a multi-disciplinary research center with various current translational studies with a focus on the study of HIV persistence (latency mechanisms, immune response, drug development, viral clearance, novel assays, approaches, and therapeutics). Specifically, the Synthetic Organic Chemist will lead chemistry initiatives to discover and develop novel agents that will reverse HIV latency.
The position will be expected to define project goals and experimental plans in consultation with the Principal Investigator (Pl). The position will be responsible for contributing to the design of biologically active compounds, planning (and execution) of synthetic routes, and the interpretation of biological results. This position will involve interpreting data to help inform strategy and decision making to progress project goals. The position will be responsible for the preparation, purification, and characterization of all materials, maintaining clear and current records of their work within an electronic laboratory notebook and will perform all applicable analytical work.
The position will also serve as the technical expert, supporting Cure Center members working in the lab by assisting with laboratory duties and assays when necessary. Additionally, this position will collaborate with Pl and collaborators in the publication and presentation of research findings.
This is a time-limited position with an estimated duration of 1 year.
Education and Experience:
Bachelor’s degree in a discipline related to the area of assignment; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.
The ideal candidate must have expertise in synthetic organic chemistry and will be expected to work with faculty, staff, and collaborators to facilitate translational research at the clinical/basic science interface. Able to manage early-stage drug discovery efforts to successful candidate selection. Able to manage outsourced Contract Research Organization (CRO) programs developing compounds for testing inappropriate in vitro and in vivo models.
The ideal candidate must be able to design biologically active compounds, plan and execute synthetic routes, and then interpret the biological results. The candidate must be skilled in the preparation, purification and characterization of all materials, must maintain clear and current records of their work within an electronic laboratory notebook and must perform all applicable analytical work.
The ideal candidate must have the ability to work independently with little to no guidance from the Pl and senior scientific leadership. Must have the ability to independently oversee the work of postdoctoral associated. Able to provide technical expertise in the design and synthesis of molecules to all Cure Center scientists.
Must have strong interpersonal, verbal, and written communication skills. Able to develop and deliver presentations, publications to communicate the results of the research program.
Candidate must possess flexibility, mobility, and strength to move and access research samples, reagents, and supplies. Needs to have the physical ability to perform many varied tasks: i.e. fine motor skills, excellent hand-eye coordination, and a high level of concentration to do challenging and detailed technical work.
BS in Chemistry or related field is strongly preferred. 5+ years of synthetic organic chemistry experience strongly preferred. Knowledge of basic science models of HIV or other viral infections.
Experience with Drug Metabolism and Pharmacokinetics (DMPK) studies and the characterization of absorption, distribution, metabolism, and excretion (ADME) properties of drug candidates.
Familiarity with polymer chemistry, protein characterization, and formulation development.
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.
Internal Number: 158161
About The University of North Carolina at Chapel Hill
Carolina rates among the nation’s great institutions of higher education, set on an historic and beautiful campus that celebrates all four seasons. Carolina’s students, faculty and staff come here from around the world, bringing varied cultural, racial and ethnic heritages that help make UNC-Chapel Hill a thriving intellectual center. We’re repeatedly ranked the nation’s best value in higher education for students seeking to earn a college degree – the University has garnered the top spot each time since the ranking’s launch in 1998.Whether you’ve just started your career, are new to academia or are a seasoned professional with assorted campus experiences to draw on, we hope you will find a great place at Carolina.