Research - Laboratory/Non-Laboratory, Staff/Administrative
The Center for Neurogastroenterology is looking for a Sr. Research Data Scientist (Data Analyst or Bioinformatician) to take the lead in several exciting projects on analyzing genomics data from the gastrointestinal tract. The successful candidate will have a PhD or Masters in computational biology, biostatistics, biomedical engineering, applied mathematics, or a related field and will have proficiency in programming experience with R/Bioconductor and/or Python for analyzing high-throughput genomics data. The candidate should have experience with high-performance computing clusters and LINUX scripting and have problem-solving skills and independence. The candidate will work collaboratively with a team of wet lab and other data scientists to create a molecular taxonomy of the cells that are present in the gastrointestinal tract and the neurons that innervate the gut in both healthy and diseased animal models and from human tissue. Using data from single-cell and bulk RNA-sequencing technologies, the candidate will work with the multi-disciplinary team to analyze this data and generate hypothesis to drive the next generation of wet lab biology and in vivo experiments. The position requires a highly-motivated applicant with fluency in spoken and written English.
Specific duties & responsibilities:
Work in collaboration with scientists and core staff to address research questions involving the data migration, management, and analysis of next-generation sequencing data. Using systems biology methodology to integrate multiple datasets.
Performs analyses independently.
Designs and oversees multiple extensive databases that integrate biological and molecular data from the laboratory and from collaborators.
Contribute to the local protocol development and the preparation of research grant applications in this collaborative setting.
Discuss with colleagues, investigators, and supervise the need for any additional analyses and/or special methodologic needs.
Prepare written reports of statistical analyses, including relevant statistical theory, references, methods, results, and conclusions.
Responsible for co-authorship of manuscripts, and critical readings of most grants and manuscripts.
Design, build, maintain and run software pipelines for aligning and performing statistical analyses on very large collections of DNA and RNA sequencing data such as the Tuxedo suite (Bowtie, Tophat, etc.).
Work with biologists and statisticians to develop novel software to address specific bioinformatics questions. (Proficiency in R or Python is preferred)
Responsible for preparation of data files and reports to assist fellow project members.
Identify systematic problems with data related to lab or data cleaning methods, software, or personnel.
Keep abreast of technical and academic resources related to the methodology of statistical analyses.
Interface with principal-investigator and collaborators in providing laboratory data—including format design, data systems, etc.
This position will also understand the existing protocols and develop protocols for the various studies as well as update and change the protocol for the studies as necessary.
Develop and maintain research project laboratory databases.
Master's degree in a related discipline, one year related experience and highly specialized advanced knowledge, education and/or training in specialized field of study to conduct research required. Demonstrated ability on significant graduate project or additional doctoral education may substitute for experience to the extent permitted by the JHU equivalency formula.
30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
Classified Title: Sr. Research Data Analyst Role/Level/Range: ACRP/04/MD Salary: $51,975 - $71,497
Department name: 10002808-SOM DOM Gastroenterology Work Schedule/Hours: M-F, 8:30 am-5:00 pm Location: 720 Rutland Avenue Personnel area: School of Medicine
The successful candidate(s) for this position will be subject to a pre-employment background check.
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