Interested applicants should submit a cover letter, a CV and contact information for three references.
The research lab of Dr. Michael Holinstat in the Department of Pharmacology at the University of Michigan, Ann Arbor, MI is in search of a postdoctoral Research Fellow. The selected candidate will investigate platelet biochemical and physiological steps in the regulation of blood coagulation in vitro, ex vivo, and in vivo by fatty acid lipid regulators. They will be afforded the ability to work in an open-lab environment with access to all of its state-of-the-art equipment in order to gain a greater understanding of hemostasis and thrombosis in the in vivo, in vitro, and ex vivo setting in both human and small animal models.
The lab maintains state-of-the-art hemostasis and thrombosis facilities including lumi-aggregometers, flow cytometer, hemavet, a microscopy facility containing 2 zeiss microscopes with the capacity for in vivo intravital confocal microscopy and single-cell high resolution microscopy, PCR machines, a multi-mode plate reader, and a phlebotomy suite with full-time phlebotomist. The lab is situated in the heart of Michigan Medicine within steps of a multitude of research resources and easy access to collaborators, the clinics, and animal facilities.
The project the selected candidate will focus on is the regulation of platelets in health and cardiovascular disease. In particular, how fatty acids can regulate platelet reactivity leading to myocardial infarction (MI) and stroke is a major focus of the lab. They will test novel anti-platelet therapeutics for minimizing thrombosis without significantly increasing the risk of bleeding using human platelet studies ex vivo and mouse models in vivo.
A PhD, MD, or MD/PhD degree is required. A background in physiology, biochemistry, molecular biology, or other related biomedical discipline is required.
Experience working with small animals is a plus. Experience with flow cytometry, western blot techniques, and working in a team environment is recommended but not required.
Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Job openings are posted for a minimum of seven calendar days. This job may be removed from posting boards and filled anytime after the minimum posting period has ended.
The University of Michigan is an equal opportunity/affirmative action employer.
Internal Number: 169782
About University of Michigan - Ann Arbor
A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.