The laboratory is focused on drug discovery translational biology in neurodevelopmental disorders such as Angelman syndrome and Rett syndrome. This position will be primarily responsible for investigating small molecules or oligonucleotides capable of activating disease-correcting genes. Of particular interest is to identify potential therapeutics, to decipher the mechanism of action of the drugs, and to develop chemical probes and therapeutics for preclinical and potential clinical applications. The individual who will fill this position will be expected to design experiments, to plan projects, and to work in the context of timelines and deliverables. These include, but not limited to, performing drug screening, orthogonal assays (e.g. cell-based, biochemical assays), PK/PD studies and other duties as needed. Additional responsibilities will include some oversight of other workers, writing grants, manuscripts, and progress reports, and maintenance of common equipment.
Education and Experience:
Must have 4 years or more of research experience in academia and/or industry labs. Must possess a multidisciplinary approach to understand the basis of neurological disorders that include: neuroscience, mouse genetics, pharmacology, chemical biology, cell biology, and biochemistry based approaches. Must be familiar with relevant literature and be able to lead preparation of publications and grant applications. Must have experience to train and supervise junior lab personnel and students. Must be able to work very independently.
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or status as a protected veteran.
Internal Number: 156835
About The University of North Carolina at Chapel Hill
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