Summary Description: Precision Medicine Postdoctoral Scholars in Columbia's Institute for Genomic Medicine The Institute for Genomic Medicine (IGM) at Columbia University Irving Medical Center is a unique interdisciplinary research environment specializing in human genetics and genomics. The IGM uses next generation sequencing technologies to sequence 20K individuals per year, and has cutting-edge programs human genetics, statistical genetics and bioinformatics, and cellular and animal models of human disease, generating over 30 million dollars per year in research funding. Postdoctoral researchers are typically mentored by more than one faculty member, offering unique opportunities for integrating basic and translational research. The Institute is actively recruiting postdoctoral research scientists to be at the forefront of the rapidly expanding field of precision medicine and therapeutic discovery in the following areas: Bioinformatics/Statistical Genetics Working with an interdisciplinary team of investigators, the successful candidate will have primary responsibilities focused the development of novel approaches of analyzing next generation sequence data and rich phenotypic information from tens of thousands of individuals to identify disease associated genomic loci and to study patterns of mutations genome-wide to discern pathogenic and benign mutations in individuals. A suitable candidate should have a doctoral degree in a quantitative field, such as bioinformatics, computational biology, statistical genetics, biostatistics or computer science, and have sufficient experience in algorithm development and scientific programming. The successful candidate will be supervised by Drs. David Goldstein, Matt Harms, and/or or Erin Heinzen (or a combination thereof), and have significant interactions with other faculty and scientists within the Institute and within the broader Columbia and NYC research community. Human genetics/Precision Medicine Working with an interdisciplinary team of investigators, the successful candidate will have primary responsibilities focused on the analysis and interpretation of genetic variation and detailed phenotypic information from patients with a range of disorders, including epilepsy, amyotrophic lateral sclerosis, schizophrenia, rare severe pediatric disorders and beyond, collected through the Columbia Precision Medicine Initiatives. A suitable candidate should have a doctoral degree in human genetics or a related field, and have extensive experience analyzing genomic datasets. The successful candidate will be supervised by Drs. David Goldstein, Matt Harms, Vimla Aggarwal, and/or Erin Heinzen (or a combination thereof), and have significant interactions with other faculty and scientists within the Institute and within the broader Columbia and NYC research community. Experimental Genetics and NeuroscienceThe successful candidate will have the opportunity to work with an interdisciplinary team of investigators to study mouseand cellular models of epilepsy and related neurological disorders, through understanding mechanisms that regulate brain development and function at physiological, behavioral and/or molecular levels. The position also provides an opportunity to combine genetic modeling with preclinical phenotyping and physiology towards the development of precision genetic therapies. A suitable candidate should have a doctoral degree in experimental biology, and direct experience with animal or cellular model systems. The successful candidate will be co-supervised by Drs. David Goldstein, Wayne Frankel, Mike Boland, Jennifer Gelinas, Yueqing Peng, and/or Erin Heinzen (or a combination thereof), and have significant interactions with other faculty and scientists within the Institute and within the broader Columbia and NYC research community.
Minimum Qualifications: Candidates should have or be very close to obtaining a Ph.D. in a relevant field, and have less than five years of postdoctoral experience.
Preferred Qualifications: Ph.D. and published one or more first author research articles in leading journals.
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Columbia University is an Equal Opportunity/Affirmative Action employer.
Internal Number: 334_66771
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.