Supported by the NIMH Psychoactive Drug Screening Program (PDSP), we are seeking a staff scientist position to join our team to collaborate on PDSP screening center. The PDSP provides screening of novel psychoactive compounds to qualified academic investigators at no cost. The main duties are to develop and carry out cell-based functional assays with the G-protein coupled receptors (GPCRs) large collection in a high throughput fashion. Specifically, the staff scientist will be involved in planning, developing and performing small and large scale screens for a myriad of drug targets including transporters, ion channels and GPCRs according to current protocols and developing new ones to address additional requests. This position will maintain multiple cell lines, prepare DNA, carry out transfection, plate cells in 96- and 384- well plates, and perform cell-based functional assays. Analyze results from the plate readers using MS Excel and Prism. The experiments will be conducted by the researcher; at times as part of a team but, for the vast majority as an individual. Results will be collected and analyzed by the staff scientist then submitted to the PDSP online database ensuring accuracy and precision. This position will report to the PDSP Assistant Scientific Director.
Education and Experience:
The ideal candidate has knowledge and experience in molecular biology, tissue culture, high-throughput screening and biochemical characterization. Must be motivated and have a strong background in biochemistry and/or structural biology. A demonstrated knowledge of GPCR signaling, molecular pharmacology and in vitro pharmacology is highly desirable.
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or status as a protected veteran.
Internal Number: 151668
About The University of North Carolina at Chapel Hill
Carolina rates among the nation’s great institutions of higher education, set on an historic and beautiful campus that celebrates all four seasons. Carolina’s students, faculty and staff come here from around the world, bringing varied cultural, racial and ethnic heritages that help make UNC-Chapel Hill a thriving intellectual center. We’re repeatedly ranked the nation’s best value in higher education for students seeking to earn a college degree – the University has garnered the top spot each time since the ranking’s launch in 1998.Whether you’ve just started your career, are new to academia or are a seasoned professional with assorted campus experiences to draw on, we hope you will find a great place at Carolina.