The Bondy-Denomy lab is seeking an Associate or Full Specialist with expertise in bioinformatics to join our group and contribute to new and ongoing projects. Our lab focuses on CRISPR-Cas immune systems and their natural functions in bacteria. We are also interested in developing new gene editing tools from Type I and II CRISPR-Cas systems, and from phage-encoded inhibitors that we have discovered (see Bondy-Denomy et al., Nature 2013, 2015, Rauch et al., Cell 2017). We are launching an effort that requires extensive bioinformatics expertise and the ability to analyze bacterial genomes and metagenomes. The candidate will be expected to contribute to this work in the lab, by leading the bioinformatics analysis and interacting with experimentalists in the group to make new discoveries. An exceptional candidate will be able to design and execute hypotheses related to novel gene function in the phage and bacterial arms race, design experiments to test ideas, and communicate these ideas to the group to plan next steps. Additionally, the specialist will be expected to assist with managing day-to-day lab operations, and perform general lab duties and be a positive lab citizen.
PhD degree in molecular genetics, microbiology, bioinformatics or related discipline is required
Two or more years of recent, directly related computational work experience utilizing techniques or methods required by the position.
Strong publication record demonstrating leadership and productivity
Excellent organizational and interpersonal communication skills (verbal and written)
Willingness and ability to learn new methods and skills for changing research priorities.
Ability to work independently and as a member of a research team.
Ability to prioritize tasks, coordinate work tasks with others, and meet multiple deadlines.
Applicants must possess the basic requirements by the time of the appointment.
Prior experience with CRISPR-Cas systems and bacteriophage
Prior experience in the design and analysis of microbiological and genetic experiments
Prior experience in bacterial genome and high throughput sequencing analysis
We are seeking at least a 1-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.
UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.